Chinese herbal medicine: Fighting SARS-CoV-2 infection on all fronts

Z Wang, L Yang - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance Severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infection causes coronavirus disease 2019 (COVID-19), a highly pathogenic virus …

Cold stress regulates accumulation of flavonoids and terpenoids in plants by phytohormone, transcription process, functional enzyme, and epigenetics

J He, L Yao, L Pecoraro, C Liu, J Wang… - Critical Reviews in …, 2023 - Taylor & Francis
Plants make different defense mechanisms in response to different environmental stresses.
One common way is to produce secondary metabolites. Temperature is the main …

Anti-SARS-CoV-2 potential of artemisinins in vitro

R Cao, H Hu, Y Li, X Wang, M Xu, J Liu… - ACS Infectious …, 2020 - ACS Publications
The discovery of novel drug candidates with anti-severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) potential is critical for the control of the global COVID-19 …

Injectable amphipathic artesunate prodrug‐hydrogel microsphere as gene/drug nano‐microplex for rheumatoid arthritis therapy

C Li, Y Du, H Lv, J Zhang, P Zhuang… - Advanced Functional …, 2022 - Wiley Online Library
Artemisinin and its derivatives (artemisinins) are first‐line chemotherapeutic agents of lethal
malaria, which also showed tremendous value in many other diseases including chronic …

Medicinal plant-derived mtDNA via nanovesicles induces the cGAS-STING pathway to remold tumor-associated macrophages for tumor regression

J Liu, J Xiang, C Jin, L Ye, L Wang, Y Gao, N Lv… - Journal of …, 2023 - Springer
Plant-derived nanovesicles (PDNVs) have been proposed as a major mechanism for the
inter-kingdom interaction and communication, but the effector components enclosed in the …

An overview of the anti-SARS-CoV-2 properties of Artemisia annua, its antiviral action, protein-associated mechanisms, and repurposing for COVID-19 treatment

AD Fuzimoto - Journal of integrative medicine, 2021 - Elsevier
Artemisia annua and its phytocompounds have a rich history in the research and treatment
of malaria, rheumatoid arthritis, systemic lupus erythematosus, and other diseases …

Synthetic biology-inspired cell engineering in diagnosis, treatment, and drug development

N Zhao, Y Song, X Xie, Z Zhu, C Duan… - … and Targeted Therapy, 2023 - nature.com
The fast-developing synthetic biology (SB) has provided many genetic tools to reprogram
and engineer cells for improved performance, novel functions, and diverse applications …

Perspectives and controversies regarding the use of natural products for the treatment of lung cancer

T Wen, L Song, S Hua - Cancer Medicine, 2021 - Wiley Online Library
Lung cancer is the leading cause of cancer‐related mortality both in men and women and
accounts for 18.4% of all cancer‐related deaths. Although advanced therapy methods have …

Research Advances on Health Effects of Edible Artemisia Species and Some Sesquiterpene Lactones Constituents

A Trendafilova, LM Moujir, PMC Sousa, AML Seca - Foods, 2020 - mdpi.com
The genus Artemisia, often known collectively as “wormwood”, has aroused great interest in
the scientific community, pharmaceutical and food industries, generating many studies on …

Antimalarial and anticancer properties of artesunate and other artemisinins: current development

P Khanal - Monatshefte für Chemie-Chemical Monthly, 2021 - Springer
This review provides a recent perspective of artesunate and other artemisinins as
antimalarial drugs and their uses in cancer therapy. Artesunate is an artemisinin derivative …