Controlled anti-cancer drug release through advanced nano-drug delivery systems: Static and dynamic targeting strategies

FM Kashkooli, M Soltani, M Souri - Journal of controlled release, 2020 - Elsevier
Advances in nanomedicine, including early cancer detection, targeted drug delivery, and
personalized approaches to cancer treatment are on the rise. For example, targeted drug …

Targeting tumor microenvironment for cancer therapy

C Roma-Rodrigues, R Mendes, PV Baptista… - International journal of …, 2019 - mdpi.com
Cancer development is highly associated to the physiological state of the tumor
microenvironment (TME). Despite the existing heterogeneity of tumors from the same or from …

Magnetic nanoparticles in cancer therapy and diagnosis

A Farzin, SA Etesami, J Quint, A Memic… - Advanced healthcare …, 2020 - Wiley Online Library
There is urgency for the development of nanomaterials that can meet emerging biomedical
needs. Magnetic nanoparticles (MNPs) offer high magnetic moments and surface‐area‐to …

To exploit the tumor microenvironment: Since the EPR effect fails in the clinic, what is the future of nanomedicine?

F Danhier - Journal of Controlled Release, 2016 - Elsevier
Tumor targeting by nanomedicine-based therapeutics has emerged as a promising
approach to overcome the lack of specificity of conventional chemotherapeutic agents and to …

Emerging nanotechnology and advanced materials for cancer radiation therapy

G Song, L Cheng, Y Chao, K Yang, Z Liu - Advanced materials, 2017 - Wiley Online Library
Radiation therapy (RT) including external beam radiotherapy (EBRT) and internal
radioisotope therapy (RIT) has been widely used for clinical cancer treatment. However …

Light in diagnosis, therapy and surgery

SH Yun, SJJ Kwok - Nature biomedical engineering, 2017 - nature.com
Light and optical techniques have made profound impacts on modern medicine, with
numerous lasers and optical devices currently being used in clinical practice to assess …

Nanoparticles-based magnetic and photo induced hyperthermia for cancer treatment

SK Sharma, N Shrivastava, F Rossi, NTK Thanh - Nano Today, 2019 - Elsevier
Nanoscience provides several modalities to combat cancer disease effectively. Magnetic
hyperthermia and photothermal therapy techniques are central research themes among …

Tumor penetrating peptides for improved drug delivery

E Ruoslahti - Advanced drug delivery reviews, 2017 - Elsevier
In vivo screening of phage libraries in tumor-bearing mice has been used to identify
peptides that direct phage homing to a tumor. The power of in vivo phage screening is …

Evolution of macromolecular complexity in drug delivery systems

A Kakkar, G Traverso, OC Farokhzad… - Nature Reviews …, 2017 - nature.com
Designing therapeutics is a process with many challenges. Even if the first hurdle—
designing a drug that modulates the action of a particular biological target in vitro—is …

Designing stimuli‐responsive upconversion nanoparticles that exploit the tumor microenvironment

M Ovais, S Mukherjee, A Pramanik, D Das… - Advanced …, 2020 - Wiley Online Library
Tailoring personalized cancer nanomedicines demands detailed understanding of the tumor
microenvironment. In recent years, smart upconversion nanoparticles with the ability to …