Blood vessels respond to injury through a healing process that includes neointimal
hyperplasia. The vascular endothelium is a monolayer of cells that separates the outer …

Notch signaling orchestrates the regulation of cell proliferation, differentiation, migration and
apoptosis of epidermal cells by strictly interacting with other cellular pathways. Any …

Endogenous repair after chronic compressive spinal cord injury (CCSCI) is of great clinical
interest. Ischemia-hypoxia-induced angiogenesis has been proposed to play an important …

Summary Interleukin (IL)-1β is now emerging as a critical cytokine in the pathogenesis of T
helper type 17 (Th17)-mediated skin diseases, including psoriasis. Psoriatic keratinocytes …

Psoriasis is a chronic inflammatory disease characterized by the abnormal differentiation
and hyperproliferation of epidermal keratinocytes. The aim of the present study was to …

Background Systemic inflammation and imbalance between endothelial injury and repair,
the latter referred to as vascular incompetence, are associated with atherosclerosis and …

Generalized pustular psoriasis (GPP), the most grievous variant of psoriasis, is featured by
dysregulated systemic inflammatory response. The cellular and molecular basis of GPP is …

Abstract Objectives Serum amyloid A (SAA), an acute phase protein, is highly expressed in
psoriatic lesions but its function is not fully understood. The aim of this study was to explore …

Hidradenitis suppurativa is a chronic, suppurative condition of the pilosebaceous unit
manifesting as painful nodules, abscesses, and sinus tracts mostly in, but not limited to …

Serum amyloid A (SAA), a major acute-phase reactant, modulates angiogenesis in many
diseases. Vascular endothelial growth factor receptor 2 (VEGFR2) is the primary angiogenic …