The diagnosis and clinical management of the neuropsychiatric manifestations of lupus

M Govoni, A Bortoluzzi, M Padovan, E Silvagni… - Journal of …, 2016 - Elsevier
Neuropsychiatric (NP) involvement in Systemic Lupus Erythematosus (SLE), can be a
severe and troubling manifestation of the disease that heavily impacts patient's health …

Laboratory and neuroimaging biomarkers in neuropsychiatric systemic lupus erythematosus: where do we stand, where to go?

C Magro-Checa, GM Steup-Beekman… - Frontiers in …, 2018 - frontiersin.org
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by
multi-systemic involvement. Nervous system involvement in SLE leads to a series of …

Serum metabolomic profiling in patients with systemic lupus erythematosus by GC/MS

B Yan, J Huang, C Zhang, X Hu, M Gao… - Modern …, 2016 - academic.oup.com
Objectives: The aim of this study is to characterize the serum metabolic profiles of patients
with systemic lupus erythematosus (SLE) using metabolomics. Methods: Serum samples …

Fecal metabolites were altered, identified as biomarkers and correlated with disease activity in patients with systemic lupus erythematosus in a GC-MS-based …

R Yan, H Jiang, S Gu, N Feng, N Zhang, L Lv… - Frontiers in …, 2020 - frontiersin.org
Gut metabolites are products of the crosstalk between microbes and their host and play an
important role in the occurrence, development, diagnosis, and treatment of autoimmune …

Increasing of blood brain barrier permeability and the association with depression and anxiety in systemic lupus erythematosus patients

X Wang, L Ma, Y Luo, Y Yang, B Upreti, Y Cheng… - Frontiers in …, 2022 - frontiersin.org
Objective To study changes in blood brain barrier (BBB) permeability in systemic lupus
erythematosus (SLE) patients, and explore the association between the alterations in BBB …

Noise-immune extreme ensemble learning for early diagnosis of neuropsychiatric systemic lupus erythematosus

Y Yuan, T Quan, Y Song, J Guan… - IEEE Journal of …, 2022 - ieeexplore.ieee.org
Early diagnosis is currently the most effective way of saving the life of patients with
neuropsychiatric systemic lupus erythematosus (NPSLE). However, it is rather difficult to …

[HTML][HTML] Relationships between brain metabolite levels, functional connectivity, and negative mood in urologic chronic pelvic pain syndrome patients compared to …

DE Harper, E Ichesco, A Schrepf, M Halvorson… - NeuroImage: Clinical, 2018 - Elsevier
Until recently, the predominant pathology of chronic pelvic pain conditions was thought to
reside in the peripheral tissues. However, mounting evidence from neuroimaging studies …

Alterations in cerebral perfusion and corresponding brain functional networks in systemic lupus erythematosus with cognitive impairment

H Liu, H Liu, B Tian, P Yang, G Fan - Scientific Reports, 2025 - nature.com
Cognitive impairment (CI) frequently occurs in patients with systemic lupus erythematosus
(SLE) and may result from neuroinflammation processes and neurovascular changes in the …

[HTML][HTML] Diminished white matter integrity in patients with systemic lupus erythematosus

T Schmidt-Wilcke, P Cagnoli, P Wang, T Schultz… - NeuroImage: Clinical, 2014 - Elsevier
Purpose Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disease
that can affect the central nervous system. Neuropsychiatric symptoms are found in 25–70 …

[HTML][HTML] Advanced and conventional magnetic resonance imaging in neuropsychiatric lupus

N Sarbu, N Bargalló, R Cervera - F1000Research, 2015 - ncbi.nlm.nih.gov
Neuropsychiatric lupus is a major diagnostic challenge, and a main cause of morbidity and
mortality in patients with systemic lupus erythematosus (SLE). Magnetic resonance imaging …