MicroRNA: function, detection, and bioanalysis
Mature microRNAs (miRNAs) are a class of evolutionally conserved, single-stranded, small
(approximately 19− 23 nucleotides), endogenously expressed, and non-protein-coding …
(approximately 19− 23 nucleotides), endogenously expressed, and non-protein-coding …
Cooperative and individualistic functions of the microRNAs in the miR-23a~ 27a~ 24-2 cluster and its implication in human diseases
The small RNA molecules of about 19-22 nucleotides in length, aptly called microRNAs,
perform the task of gene regulation in the cell. Interestingly, till the early nineties very little …
perform the task of gene regulation in the cell. Interestingly, till the early nineties very little …
Gaussia luciferase reporter assay for monitoring biological processes in culture and in vivo
BA Tannous - Nature protocols, 2009 - nature.com
Secreted reporters are a useful tool in the monitoring of different biological processes in the
conditioned medium of cultured cells as well in the blood and urine of experimental animals …
conditioned medium of cultured cells as well in the blood and urine of experimental animals …
DNA-encoded library versus RNA-encoded library selection enables design of an oncogenic noncoding RNA inhibitor
Nature evolves molecular interaction networks through persistent perturbation and selection,
in stark contrast to drug discovery, which evaluates candidates one at a time by screening …
in stark contrast to drug discovery, which evaluates candidates one at a time by screening …
Recent advances in high-performance fluorescent and bioluminescent RNA imaging probes
RNA plays an important role in life processes. Imaging of messenger RNAs (mRNAs) and
micro-RNAs (miRNAs) not only allows us to learn the formation and transcription of mRNAs …
micro-RNAs (miRNAs) not only allows us to learn the formation and transcription of mRNAs …
Molecular imaging of a cancer-targeting theragnostics probe using a nucleolin aptamer-and microRNA-221 molecular beacon-conjugated nanoparticle
JK Kim, KJ Choi, M Lee, M Jo, S Kim - Biomaterials, 2012 - Elsevier
MicroRNAs (miRNA, miR) have been reported as cancer biomarkers that regulate tumor
suppressor genes. Hence, simultaneous detecting and inhibiting of miRNA function will be …
suppressor genes. Hence, simultaneous detecting and inhibiting of miRNA function will be …
MicroRNAs‐based imaging techniques in cancer diagnosis and therapy
M Keshavarzi, S Sorayayi… - Journal of cellular …, 2017 - Wiley Online Library
Cancer is one of the most serious global health concerns in different populations. Several
studies indicated that there are many potentially promising cellular and molecular targets for …
studies indicated that there are many potentially promising cellular and molecular targets for …
The NF-κB member p65 controls glutamine metabolism through miR-23a
MG Rathore, A Saumet, JF Rossi… - The international journal …, 2012 - Elsevier
Cancer cells have elevated aerobic glycolysis that is termed the Warburg effect. But several
tumor cells, including leukemic cells, also increase glutamine metabolism, which is initiated …
tumor cells, including leukemic cells, also increase glutamine metabolism, which is initiated …
Molecular beacon-based bioimaging of multiple microRNAs during myogenesis
WJ Kang, YL Cho, JR Chae, JD Lee, KJ Choi, S Kim - Biomaterials, 2011 - Elsevier
MicroRNAs (miRNAs, miR) are associated with multiple cellular processes and diseases.
Here, we designed fluorescent DNA probes composed of stem loop-structured DNA …
Here, we designed fluorescent DNA probes composed of stem loop-structured DNA …
Gaussia Luciferase Variant for High-Throughput Functional Screening Applications
CA Maguire, NC Deliolanis, L Pike, JM Niers… - Analytical …, 2009 - ACS Publications
Gaussia luciferase (Gluc) is a sensitive reporter for studying different biological processes
such as gene expression, promoter activity, protein− protein interactions, signal …
such as gene expression, promoter activity, protein− protein interactions, signal …