Antimicrobial drugs are key tools to prevent and treat bacterial infections. Despite the early
success of antibiotics, the current treatment of bacterial infections faces serious challenges …

Bacteria have developed a wealth of strategies to avoid and resist the action of antibiotics,
one of which involves pathogens invading and forming reservoirs within host cells. Due to …

Tuberculosis (TB) is the second most deadly infectious disease. Despite potentially curative
pharmacotherapies being available for over 50years, the length of the treatment and the pill …

Infections caused by antibiotic-resistant bacteria (ARB) are one of the major global health
challenges of our time. In addition to developing new antibiotics to combat ARB, sensitizing …

Systemic administration of antitubercular drugs can be complicated by off-target toxicity to
cells and tissues that are not infected by Mycobacterium tuberculosis. Delivery of …

The aim of the research work was to develop and characterize rifampicin (RIF) loaded
gelatin nanoparticulate delivery system for the effective management of tuberculosis. Gelatin …

Nanomedicine, a promising area of medicine, employs nanosized tools for the diagnosis,
prevention, and treatment of disease. Particularly, liposomes, lipid-based nanovesicles, are …

Tuberculosis (caused by Mycobacterium tuberculosis, Mtb) treatment involves multiple drug
regimens for a prolonged period. However, the therapeutic benefit is often limited by poor …

The objective of the present study was to evaluate the prospective of engineered
nanoparticles for selective delivery of an antituberculosis drug, rifabutin, to alveolar tissues …

Leishmaniases are infectious diseases caused by an intracellular protozoan in humans by
20 different species of Leishmania among more than 53 species. There are at least twelve …