Inflammatory bowel disease (IBD) comprises a group of chronic inflammatory disorders of
the gastrointestinal tract. Accumulating evidence shows that the development of IBD is …

Epithelial tight junctions (TJs) are the key structures regulating paracellular trafficking of
macromolecules. The TJ is multi-protein complex that forms a selective permeable seal …

The gastrointestinal epithelium forms the boundary between the body and external
environment. It effectively provides a selective permeable barrier that limits the permeation …

Background The intestinal mucosa is composed of a well-organized epithelium, acting as a
physical barrier to harmful luminal contents, while simultaneously ensuring absorption of …

Although weaning stress has been reported to impair intestinal barrier function, the
mechanisms have not yet been elucidated. In the present study, the intestinal morphology …

Cytokines play a crucial role in the modulation of inflammatory response in the
gastrointestinal tract. Pro-inflammatory cytokines including tumor necrosis factor-α, interferon …

Background The associated increase in the lipopolysaccharide (LPS) levels and uremic
toxins in chronic kidney disease (CKD) has shifted the way we focus on intestinal microbiota …

The present research evaluated the effects of dietary tryptophan (Trp) on growth
performance, intestinal mucosal immune, barrier function and antioxidant capacity and gene …

The present study was carried out to evaluate the pharmacological effect of Zn in diarrhoea
in relation to intestinal permeability. Seventy-two weaning piglets, aged 24 d, were allocated …

This review is a current summary of the role that both zinc deficiency and zinc
supplementation can play in the etiology and therapy of a wide range of gastrointestinal …