Endothelial barrier integrity is required for maintaining vascular homeostasis and fluid
balance between the circulation and surrounding tissues and for preventing the …

Abstract Forkhead Box M1 (FOXM1) is a bona fide oncofoetal transcription factor, which
orchestrates complex temporal and spatial gene expression throughout embryonic and …

Aging is a major risk factor of high incidence and increased mortality of acute respiratory
distress syndrome (ARDS). Here, we demonstrated that persistent lung injury and high …

Microvesicles (MVs) derived from human mesenchymal stem cells (MSC MVs) were
demonstrated to ameliorate inflammation in lungs. We have found their content of mRNA for …

We sought to define the mechanism underlying lung microvascular regeneration in a model
of severe acute lung injury (ALI) induced by selective lung endothelial cell ablation …

The confluent pulmonary endothelium plays an important role as a semi-permeable barrier
between the vascular space of blood vessels and the underlying tissues, and it contributes …

Rationale: Increased endothelial permeability and defective repair are the hallmarks of
several vascular diseases, including acute lung injury. However, little is known about the …

Idiopathic pulmonary fibrosis (IPF) is a major cause of respiratory failure in critically ill
patients and common outcome of various lung interstitial diseases. Its mortality remains …

Bone marrow-derived mesenchymal stem cells (MSCs), which have beneficial effects in
acute lung injury (ALI), can serve as a vehicle for gene therapy. Angiotensin-converting …

Systemic lupus erythematosus (SLE) is a multi-system autoimmune disease including the
cardiovascular system. Atherosclerosis is the most common cardiovascular complication of …