[HTML][HTML] Challenges and opportunities for the adoption of molecular diagnostics for anthelmintic resistance

AC Kotze, JS Gilleard, SR Doyle, RK Prichard - International Journal for …, 2020 - Elsevier
Anthelmintic resistance is a significant threat to livestock production systems worldwide and
is emerging as an important issue in companion animal parasite management. It is also an …

The mRNA vaccine technology era and the future control of parasitic infections

H You, MK Jones, CA Gordon… - Clinical Microbiology …, 2023 - Am Soc Microbiol
Despite intensive long-term efforts, with very few exceptions, the development of effective
vaccines against parasitic infections has presented considerable challenges, given the …

New paradigms in research on Dirofilaria immitis

TG Geary - Parasites & Vectors, 2023 - Springer
Background Since the advent of ivermectin (along with melarsomine and doxycycline),
heartworm has come to be viewed as a solved problem in veterinary medicine, diminishing …

Anthelmintics in the environment: Their occurrence, fate, and toxicity to non-target organisms

I Vokřál, R Podlipná, P Matoušková, L Skálová - Chemosphere, 2023 - Elsevier
Anthelmintics are drugs used for the treatment and prevention of diseases caused by
parasitic worms (helminths). While the importance of anthelmintics in human as well as in …

Evaluation of anthelmintic and anti-inflammatory activity of 1, 2, 4-triazole derivatives

R Paprocka, P Kołodziej, M Wiese-Szadkowska… - Molecules, 2022 - mdpi.com
Parasitic diseases, caused by intestinal helminths, remain a very serious problem in both
human and veterinary medicine. While searching for new nematicides we examined a series …

Selective control of parasitic nematodes using bioactivated nematicides

AR Burns, RJ Baker, M Kitner, J Knox, B Cooke… - Nature, 2023 - nature.com
Parasitic nematodes are a major threat to global food security, particularly as the world
amasses 10 billion people amid limited arable land,,–. Most traditional nematicides have …

Essential oils as novel anthelmintic drug candidates

SK Panda, M Daemen, G Sahoo, W Luyten - Molecules, 2022 - mdpi.com
Helminths, with an estimated 1.5 billion annual global infections, are one of the major health
challenges worldwide. The current strategy of the World Health Organization to prevent …

Traditional medicinal plants in the treatment of gastrointestinal parasites in humans: A systematic review and meta‐analysis of clinical and experimental evidence

S Ranasinghe, S Aspinall, A Beynon… - Phytotherapy …, 2023 - Wiley Online Library
Gastrointestinal (GI) parasites cause significant morbidity and mortality worldwide. The use
of conventional antiparasitic drugs is often inhibited due to limited availability, side effects or …

Multipurpose peptides: the venoms of Amazonian stinging ants contain anthelmintic ponericins with diverse predatory and defensive activities

SA Nixon, SD Robinson, AJ Agwa, AA Walker… - Biochemical …, 2021 - Elsevier
In the face of increasing drug resistance, the development of new anthelmintics is critical for
controlling nematodes that parasitise livestock. Although hymenopteran venom toxins have …

Egg-laying and locomotory screens with C. elegans yield a nematode-selective small molecule stimulator of neurotransmitter release

S Harrington, JJ Knox, AR Burns, KL Choo… - Communications …, 2022 - nature.com
Nematode parasites of humans, livestock and crops dramatically impact human health and
welfare. Alarmingly, parasitic nematodes of animals have rapidly evolved resistance to …