Regulation of immune homeostasis, inflammation, and HIV persistence by the microbiome, short-chain fatty acids, and bile acids
AB Enriquez, F Ten Caten, K Ghneim… - Annual review of …, 2023 - annualreviews.org
Despite antiretroviral therapy (ART), people living with human immunodeficiency virus
(HIV)(PLWH) continue to experience chronic inflammation and immune dysfunction, which …
(HIV)(PLWH) continue to experience chronic inflammation and immune dysfunction, which …
[HTML][HTML] Markers of fungal translocation are elevated during post-acute sequelae of SARS-CoV-2 and induce NF-κB signaling
Long COVID, a type of post-acute sequelae of SARS-CoV-2 (PASC), has been associated
with sustained elevated levels of immune activation and inflammation. However, the …
with sustained elevated levels of immune activation and inflammation. However, the …
Gut Leakage of Fungal‐Related Products: Turning Up the Heat for HIV Infection
The intestinal epithelial layer serves as a physical and functional barrier between the
microbiota in the lumen and immunologically active submucosa. Th17 T-cell function …
microbiota in the lumen and immunologically active submucosa. Th17 T-cell function …
Minority report: the intestinal mycobiota in systemic infections
Highlights•The human mycobiota contains clinically relevant fungal species.•Longitudinal
sampling provides robust insights into the human mycobiota.•Simultaneous analysis of …
sampling provides robust insights into the human mycobiota.•Simultaneous analysis of …
Altered intestinal permeability and fungal translocation in Ugandan children with human immunodeficiency virus
S Dirajlal-Fargo, V El-Kamari, L Weiner… - Clinical Infectious …, 2020 - academic.oup.com
Background Children with perinatally acquired human immunodeficiency virus (HIV; PHIVs)
face a lifelong cumulative exposure to HIV and antiretroviral therapy (ART). The relationship …
face a lifelong cumulative exposure to HIV and antiretroviral therapy (ART). The relationship …
[HTML][HTML] Altered mitochondrial respiration in peripheral blood mononuclear cells of post-acute sequelae of SARS-CoV-2 infection
Peripheral blood mononuclear cells (PBMC) mitochondrial respiration was measured ex
vivo from participants without a history of COVID (n= 19), with a history of COVID and full …
vivo from participants without a history of COVID (n= 19), with a history of COVID and full …
Blood Aspergillus PCR: the good, the bad, and the ugly
Invasive Aspergillosis (IA) is one of the most common invasive fungal diseases and is
accompanied by high morbidity and mortality. In order to maximize patient outcomes and …
accompanied by high morbidity and mortality. In order to maximize patient outcomes and …
Glucan rich nutrition does not increase gut translocation of beta‐glucan
Abstract Background (1‐3)‐b‐D‐glucan (BDG) is a fungal cell wall component and, in the
absence of invasive fungal infection, a novel biomarker for microbial translocation of …
absence of invasive fungal infection, a novel biomarker for microbial translocation of …
Persistent immune activation and altered gut integrity over time in a longitudinal study of Ugandan youth with perinatally acquired HIV
S Dirajlal-Fargo, M Strah, K Ailstock, A Sattar… - Frontiers in …, 2023 - frontiersin.org
Introduction Perinatally acquired HIV infection (PHIV) occurs during a critical window of
immune development. We investigated changes in systemic inflammation and immune …
immune development. We investigated changes in systemic inflammation and immune …
Walk on the wild side: SIV infection in African non-human primate hosts—from the field to the laboratory
AJ Jasinska, C Apetrei, I Pandrea - Frontiers in Immunology, 2023 - frontiersin.org
HIV emerged following cross-species transmissions of simian immunodeficiency viruses
(SIVs) that naturally infect non-human primates (NHPs) from Africa. While HIV replication …
(SIVs) that naturally infect non-human primates (NHPs) from Africa. While HIV replication …