The gut virome: A new microbiome component in health and disease

Z Cao, N Sugimura, E Burgermeister, MP Ebert… - …, 2022 - thelancet.com
The human gastrointestinal tract harbours an abundance of viruses, collectively known as
the gut virome. The gut virome is highly heterogeneous across populations and is linked to …

Metabolic and biogeochemical consequences of viral infection in aquatic ecosystems

AE Zimmerman, C Howard-Varona… - Nature Reviews …, 2020 - nature.com
Ecosystems are controlled by 'bottom-up'(resources) and 'top-down'(predation) forces. Viral
infection is now recognized as a ubiquitous top-down control of microbial growth across …

Bacteriophage trigger antiviral immunity and prevent clearance of bacterial infection

JM Sweere, JD Van Belleghem, H Ishak, MS Bach… - Science, 2019 - science.org
INTRODUCTION We have identified previously unsuspected, directly pathogenic roles for
bacteriophage (phage) virions in bacterial infections. In particular, we report that …

Cryptic inoviruses revealed as pervasive in bacteria and archaea across Earth's biomes

S Roux, M Krupovic, RA Daly, AL Borges… - Nature …, 2019 - nature.com
Bacteriophages from the Inoviridae family (inoviruses) are characterized by their unique
morphology, genome content and infection cycle. One of the most striking features of …

Bacteriophages and the immune system

M Popescu, JD Van Belleghem… - Annual review of …, 2021 - annualreviews.org
Bacteriophages—viruses that infect bacteria—are abundant within our bodies, but their
significance to human health is only beginning to be explored. Here, we synthesize what is …

Rapid colorimetric detection of bacterial species through the capture of gold nanoparticles by chimeric phages

H Peng, IA Chen - Acs Nano, 2018 - ACS Publications
Rapid, inexpensive, and sensitive detection of bacterial pathogens is an important goal for
several aspects of human health and safety. We present a simple strategy for detecting a …

Black box of phage–bacterium interactions: Exploring alternative phage infection strategies

S Mäntynen, E Laanto, HM Oksanen… - Open …, 2021 - royalsocietypublishing.org
The canonical lytic–lysogenic binary has been challenged in recent years, as more
evidence has emerged on alternative bacteriophage infection strategies. These infection …

Engineered bacteriophage therapeutics: rationale, challenges and future

M Łobocka, K Dąbrowska, A Górski - BioDrugs, 2021 - Springer
The current problems with increasing bacterial resistance to antibacterial therapies, resulting
in a growing frequency of incurable bacterial infections, necessitates the acceleration of …

Diversity of phage infection types and associated terminology: the problem with 'Lytic or lysogenic'

Z Hobbs, ST Abedon - FEMS microbiology letters, 2016 - academic.oup.com
Bacteriophages, or phages, are viruses of members of domain Bacteria. These viruses play
numerous roles in shaping the diversity of microbial communities, with impact differing …

Filamentous phages: masters of a microbial sharing economy

ID Hay, T Lithgow - EMBO reports, 2019 - embopress.org
Abstract Bacteriophage (“bacteria eaters”) or phage is the collective term for viruses that
infect bacteria. While most phages are pathogens that kill their bacterial hosts, the …