Glutathione-depleting nanomedicines for synergistic cancer therapy

X Cheng, HD Xu, HH Ran, G Liang, FG Wu - ACS nano, 2021 - ACS Publications
Cancer cells frequently exhibit resistance to various molecular and nanoscale drugs, which
inevitably affects the drugs' therapeutic outcomes. Overexpression of glutathione (GSH) has …

Biochemical pathways of copper complexes: Progress over the past 5 years

S Zehra, S Tabassum, F Arjmand - Drug Discovery Today, 2021 - Elsevier
Highlights•Overview of copper complexes as potent anticancer chemotherapeutic
agents.•Copper complexes are endogenously biocompatible and exhibit reduced side …

Enantiomeric amino acid schiff base copper (II) complexes as a new class of RNA-targeted metallo-intercalators: Single X-ray crystal structural details, comparative in …

S Zehra, T Roisnel, F Arjmand - ACS Omega, 2019 - ACS Publications
Chiral enantiomeric amino acid Schiff base copper (II) complexes 1 and 2 (a and b) were
synthesized and characterized by various spectroscopic techniques (Fourier transform …

Copper complexes as artificial DNA metallonucleases: from Sigman's reagent to next generation anti-cancer agent?

TJP McGivern, S Afsharpour, CJ Marmion - Inorganica Chimica Acta, 2018 - Elsevier
Platinum drugs continue to dominate medical oncology treatments but they have
shortcomings associated with their use including dose-limiting toxic side effects and …

Simple synthesis of novel copper metal–organic framework nanoparticles: biosensing and biological applications

SM Sheta, SM El-Sheikh, MM Abd-Elzaher - Dalton transactions, 2018 - pubs.rsc.org
Novel copper metal organic framework nanoparticles Cu-MOF-NPs (C1) were prepared via
two simple alternative methods and confirmed by analytical characterization using mass, IR …

Progress of Metal‐Based Anticancer Chemotherapeutic Agents in Last two Decades and their Comprehensive Biological (DNA/RNA Binding, Cleavage and …

F Arjmand, H Yasir Khan, S Tabassum - The Chemical Record, 2023 - Wiley Online Library
During last two decades, there has been an enormous growth in the discovery of innovative
active inorganic anticancer complexes (exerting remarkable cytotoxicity at sub micro‐molar …

Metal complexes or chelators with ROS regulation capacity: Promising candidates for cancer treatment

X Li, Y Wang, M Li, H Wang, X Dong - Molecules, 2021 - mdpi.com
Reactive oxygen species (ROS) are rapidly eliminated and reproduced in organisms, and
they always play important roles in various biological functions and abnormal pathological …

Photosensitization in highly luminescent nonmacrocyclic Samarium (III) complexes for application in light-emitting systems

A Chauhan, R Langyan - Journal of Photochemistry and Photobiology A …, 2022 - Elsevier
The synthesis of highly luminescent Samarium (III) complexes based on 6, 8-
Dichlorochromone-3-carboxaldehyde (L) and other heterocyclic ligands is described. The …

Mixed-ligand copper (ii)-diimine complexes of 3-formylchromone-N 4-phenyl thiosemicarbazone: 5, 6-dmp co-ligand confers enhanced cytotoxicity

A Mamindla, D Murugan, M Varadhan, T Ajaykamal… - RSC …, 2024 - pubs.rsc.org
The promising biological applications of thiosemicarbazone derivatives have inspired the
design, synthesis, and study of their Cu (II) complexes for anticancer therapeutic …

Heteroleptic copper (I) complexes of “scorpionate” bis-pyrazolyl carboxylate ligand with auxiliary phosphine as potential anticancer agents: An insight into cytotoxic …

RA Khan, M Usman, R Dhivya, P Balaji, A Alsalme… - Scientific reports, 2017 - nature.com
New copper (I) complexes [CuCl (PPh3)(L)](1: L= LA= 4-carboxyphenyl) bis (3, 5-
dimethylpyrazolyl) methane;(2: L= LB= 3-carboxyphenyl) bis (3, 5-dimethylpyrazolyl) …