[HTML][HTML] Bacteriophage-antibiotic combination therapy against extensively drug-resistant Pseudomonas aeruginosa infection to allow liver transplantation in a toddler

B Van Nieuwenhuyse, D Van der Linden… - Nature …, 2022 - nature.com
Post-operative bacterial infections are a leading cause of mortality and morbidity after
ongoing liver transplantation. Bacteria causing these infections in the hospital setting can …

Healthcare as a driver, reservoir and amplifier of antimicrobial resistance: opportunities for interventions

D Cocker, G Birgand, N Zhu… - Nature Reviews …, 2024 - nature.com
Antimicrobial resistance (AMR) is a global health challenge that threatens humans, animals
and the environment. Evidence is emerging for a role of healthcare infrastructure …

Current viewpoint on the epidemiology of nonfermenting Gram-negative bacterial strains

D Koulenti, KE Vandana, J Rello - Current opinion in infectious …, 2023 - journals.lww.com
The exploration of the epidemiology, as well as the pathogenic potential of the of the less
frequent, but emerging and increasingly reported NFGNB, is crucial, not only for …

Intensive care unit sinks are persistently colonized with multidrug resistant bacteria and mobilizable, resistance-conferring plasmids

L Diorio-Toth, MA Wallace, CW Farnsworth, B Wang… - Msystems, 2023 - Am Soc Microbiol
Contamination of hospital sinks with microbial pathogens presents a serious potential threat
to patients, but our understanding of sink colonization dynamics is largely based on infection …

[HTML][HTML] Potential sources of contamination on textiles and hard surfaces identified as high-touch sites near the patient environment

E Nygren, L Gonzales Strömberg, J Logenius… - Plos one, 2023 - journals.plos.org
The hospital environment represents an important mediator for the transmission of
healthcare-associated infections through direct and indirect hand contact with hard surfaces …

Nosocomial transmission of multi-drug-resistant organisms in Ukrainian hospitals: results of a multi-centre study (2019–2021)

A Salmanov, D Shchehlov, V Artyomenko… - Journal of Hospital …, 2023 - Elsevier
Background The increasing emergence and spread of multi-drug-resistant organisms
(MDROs) in hospitals is a public health problem and continues to challenge infection control …

[HTML][HTML] Environmental contamination across multiple hospital departments with multidrug-resistant bacteria pose an elevated risk of healthcare-associated infections …

E Odoyo, D Matano, F Tiria, M Georges… - … Resistance & Infection …, 2023 - Springer
Abstract Background Healthcare-associated infections (HAIs) are often caused by multidrug-
resistant (MDR) bacteria contaminating hospital environments which can cause outbreaks …

[HTML][HTML] Early life exposure of infants to benzylpenicillin and gentamicin is associated with a persistent amplification of the gut resistome

DV Patangia, G Grimaud, CA O'Shea, CA Ryan… - Microbiome, 2024 - Springer
Background Infant gut microbiota is highly malleable, but the long-term longitudinal impact
of antibiotic exposure in early life, together with the mode of delivery on infant gut microbiota …

The ICU environment contributes to the endemicity of the “Serratia marcescens complex” in the hospital setting

S Aracil-Gisbert, MD Fernández-De-Bobadilla… - Mbio, 2024 - Am Soc Microbiol
Serratia marcescens is an opportunistic pathogen historically associated with sudden
outbreaks in intensive care units (ICUs) and the spread of carbapenem-resistant genes …

From Petri Dishes to Patients to Populations: Scales and Evolutionary Mechanisms Driving Antibiotic Resistance

C Souque, I González Ojeda… - Annual Review of …, 2024 - annualreviews.org
Tackling the challenge created by antibiotic resistance requires understanding the
mechanisms behind its evolution. Like any evolutionary process, the evolution of …