Heat shock proteins (HSPs) are a large group of chaperones found in most eukaryotes and
bacteria. They are responsible for the correct protein folding, protection of the cell against …

Stress proteins (SPs) including heat-shock proteins (HSPs), RNA chaperones, and ER
associated stress proteins are molecular chaperones essential for cellular homeostasis. The …

The molecular chaperone Hsp90 (90 kDa heat-shock protein) is a remarkably versatile
protein involved in the stress response and in normal homoeostatic control mechanisms. It …

Viruses are intracellular pathogens responsible for a vast number of human diseases. Due
to their small genome size, viruses rely primarily on the biosynthetic apparatus of the host for …

Direct‐acting antiviral agents (DAAs) represent a class of drugs targeting viral proteins and
have been demonstrated to be very successful in combating viral infections in clinic …

The temperature of a solid tumor is often dissimilar to baseline body temperature and,
compared to healthy tissues, may be elevated, reduced, or a mix of both. The temperature of …

Many plus-strand (+) RNA viruses co-opt protein chaperones from the host cell to assist the
synthesis, localization and folding of abundant viral proteins, to regulate viral replication via …

Sugarcane mosaic virus (SCMV) causes substantial losses of grain yield and forage
biomass in susceptible maize worldwide. A major quantitative trait locus, Scmv1, has been …

The emergence of antiviral drug-resistant mutants is the most important issue in current
antiviral therapy. As obligate parasites, viruses require host factors for efficient replication …

Infectious organisms have to cope with demanding and rapidly changing environments
during establishment in the host. This is particularly relevant for pathogens that utilize …