The incidence of heart failure is primarily flat or declining for a presumably reflecting better
management of cardiovascular diseases, but that of heart failure with preserved ejection …

Aging biomarkers are a combination of biological parameters to (i) assess age-related
changes,(ii) track the physiological aging process, and (iii) predict the transition into a …

Aims Sodium‐glucose cotransporter 2 (SGLT2) inhibitors have been shown to be an
effective therapy in improving heart failure outcomes. We conducted a meta‐analysis of …

Heart failure (HF) is a leading cause of morbidity and mortality particularly in older adults
and patients with multiple metabolic comorbidities. Heart failure with preserved ejection …

Heart failure (HF) is a heterogeneous condition that can be categorized according to the left
ventricular ejection fraction (EF) into HF with reduced (HFrEF) or preserved (HFpEF) EF …

Heart failure with preserved ejection fraction (HFpEF) is defined as HF with left ventricular
ejection fraction (LVEF) not less than 50%. HFpEF accounts for more than 50% of all HF …

The risk of developing chronic illnesses and disabilities is increasing with age. To predict
and prevent aging, biomarkers relevant to the aging process must be identified. This paper …

Diastolic dysfunction (DD) refers to abnormalities in the mechanical function of the left
ventricle (LV) during diastole. Severe LVDD can cause symptoms and the signs of heart …

Cardiovascular diseases are the leading cause of mortality in the world. Heart failure with
preserved ejection fraction (HFpEF) accounts for about half of all heart failure. Unfortunately …

Aims: HFA-PEFF score has been proposed for diagnosing heart failure with preserved
ejection fraction (HFpEF). Currently, there are only a limited number of tools for predicting …