Current models of the mode of action of Bacillus thuringiensis insecticidal crystal proteins: a critical review

V Vachon, R Laprade, JL Schwartz - Journal of invertebrate pathology, 2012 - Elsevier
Bacillus thuringiensis (Bt) Cry toxins constitute the active ingredient in the most widely used
biological insecticides and insect-resistant transgenic crops. A clear understanding of their …

Mode of Action and Specificity of Bacillus thuringiensis Toxins in the Control of Caterpillars and Stink Bugs in Soybean Culture

R Schünemann, N Knaak… - International Scholarly …, 2014 - Wiley Online Library
The bacterium Bacillus thuringiensis (Bt) produces delta‐endotoxins that possess toxic
properties and can be used as biopesticides, as well as a source of genes for the …

Continuous evolution of Bacillus thuringiensis toxins overcomes insect resistance

AH Badran, VM Guzov, Q Huai, MM Kemp… - Nature, 2016 - nature.com
The Bacillus thuringiensis δ-endotoxins (Bt toxins) are widely used insecticidal proteins in
engineered crops that provide agricultural, economic, and environmental benefits. The …

Role of alkaline phosphatase from Manduca sexta in the mechanism of action of Bacillus thuringiensis Cry1Ab toxin

I Arenas, A Bravo, M Soberón, I Gómez - Journal of biological chemistry, 2010 - ASBMB
Cry toxins produced by Bacillus thuringiensis have been recognized as pore-forming toxins
whose primary action is to lyse midgut epithelial cells in their target insect. In the case of the …

Recent trends of modern bacterial insecticides for pest control practice in integrated crop management system

P Chattopadhyay, G Banerjee, S Mukherjee - 3 Biotech, 2017 - Springer
Food security and safety are the major concern in ever expanding human population on the
planet earth. Each and every year insect pests cause a serious damage in agricultural field …

[HTML][HTML] Pore formation: an ancient yet complex form of attack

I Iacovache, FG van der Goot, L Pernot - Biochimica et Biophysica Acta …, 2008 - Elsevier
Bacteria, as well as higher organisms such as sea anemones or earthworms, have
developed sophisticated virulence factors such as the pore-forming toxins (PFTs) to mount …

Which is stronger? A continuing battle between Cry toxins and insects

L Liu, Z Li, X Luo, X Zhang, SH Chou, J Wang… - Frontiers in …, 2021 - frontiersin.org
In this article, we review the latest works on the insecticidal mechanisms of Bacillus
thuringiensis Cry toxins and the resistance mechanisms of insects against Cry toxins …

An overview of the safety and biological effects of Bacillus thuringiensis Cry toxins in mammals

N Rubio‐Infante… - Journal of applied …, 2016 - Wiley Online Library
Crystal proteins (Cry) produced during the growth and sporulation phases of Bacillus
thuringiensis (Bt) bacterium are known as delta endotoxins. These toxins are being used …

Genetically modifying the insect gut microbiota to control Chagas disease vectors through systemic RNAi

ML Taracena, PL Oliveira, O Almendares… - PLoS neglected …, 2015 - journals.plos.org
Technologies based on RNA interference may be used for insect control. Sustainable
strategies are needed to control vectors of Chagas disease such as Rhodnius prolixus. The …

Parasporin-2 from a New Bacillus thuringiensis 4R2 Strain Induces Caspases Activation and Apoptosis in Human Cancer Cells

K Brasseur, P Auger, E Asselin, S Parent, JC Côté… - PLoS …, 2015 - journals.plos.org
In previous studies, parasporin-2Aa1, originally isolated from Bacillus thuringiensis strain
A1547, was shown to be cytotoxic against specific human cancer cells but the mechanisms …