The feeding process is required for basic life, influenced by environment cues and tightly
regulated according to demands of the internal milieu by regulatory brain circuits. Although …

In the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, binge-eating
disorder (BED) is classified as episodes of binge eating while not being hungry, eating too …

Feeding behaviors depend on intrinsic and extrinsic factors including genetics, food
palatability, and the environment. 1, 2, 3, 4, 5 The gut microbiota is a major environmental …

Casein kinases are a large family of intracellular serine/threonine kinases that control a
variety of cellular signaling functions. Here we report that a member of casein kinase 1 …

Metabolic hormones stabilize brain reward and motivational circuits, whereas excessive
opioid consumption counteracts this effect and may impair metabolic function. Here we …

Binge eating (BE) is a heritable trait associated with eating disorders and involves episodes
of rapid, large amounts of food consumption. We previously identified cytoplasmic FMR1 …

Abstract Opioid Use Disorder (OUD) and opioid‐related deaths remain a major public health
concern in the United States. Both environmental and genetic factors influence risk for OUD …

This paper is the fortieth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

Binge eating is a heritable symptom of eating disorders with an unknown genetic etiology.
Rodent models for binge-like eating (BLE) of palatable food permit the study of genetic and …

We previously identified a 210 kb region on chromosome 11 (50.37-50.58 Mb, mm10)
containing two protein-coding genes (Hnrnph1, Rufy1) that was necessary for reduced …