[HTML][HTML] Polymeric micelles in drug delivery: An insight of the techniques for their characterization and assessment in biorelevant conditions

M Ghezzi, S Pescina, C Padula, P Santi… - Journal of Controlled …, 2021 - Elsevier
Polymeric micelles, ie aggregation colloids formed in solution by self-assembling of
amphiphilic polymers, represent an innovative tool to overcome several issues related to …

Label-free isolation of exosomes using microfluidic technologies

S Hassanpour Tamrin, A Sanati Nezhad, A Sen - ACS nano, 2021 - ACS Publications
Exosomes are cell-derived structures packaged with lipids, proteins, and nucleic acids. They
exist in diverse bodily fluids and are involved in physiological and pathological processes …

Current hurdles to the translation of nanomedicines from bench to the clinic

S Đorđević, MM Gonzalez, I Conejos-Sánchez… - Drug delivery and …, 2022 - Springer
The field of nanomedicine has significantly influenced research areas such as drug delivery,
diagnostics, theranostics, and regenerative medicine; however, the further development of …

Engineered nanomaterials: The challenges and opportunities for nanomedicines

F Albalawi, MZ Hussein, S Fakurazi… - International journal of …, 2021 - Taylor & Francis
The emergence of nanotechnology as a key enabling technology over the past years has
opened avenues for new and innovative applications in nanomedicine. From the business …

Asymmetric-flow field-flow fractionation for measuring particle size, drug loading and (in) stability of nanopharmaceuticals. The joint view of European Union …

F Caputo, D Mehn, JD Clogston, M Rösslein… - … of Chromatography A, 2021 - Elsevier
Asymmetric-flow field-flow fractionation (AF4) has been recognized as an invaluable tool for
the characterisation of particle size, polydispersity, drug loading and stability of …

[HTML][HTML] Methodological needs in the quality and safety characterisation of nanotechnology-based health products: Priorities for method development and …

B Halamoda-Kenzaoui, RJ Vandebriel… - Journal of Controlled …, 2021 - Elsevier
Nanotechnology-based health products are providing innovative solutions in health
technologies and the pharmaceutical field, responding to unmet clinical needs. However …

[HTML][HTML] Field-flow fractionation for molecular-interaction studies of labile and complex systems: A critical review

IK Ventouri, S Loeber, GW Somsen… - Analytica chimica …, 2022 - Elsevier
Asymmetrical flow field-flow fractionation (AF4) has attracted considerable attention as a
size-based separation technique, due to its mild separation conditions, broad working range …

[HTML][HTML] Improved multidetector asymmetrical-flow field-flow fractionation method for particle sizing and concentration measurements of lipid-based nanocarriers for …

R Mildner, S Hak, J Parot, A Hyldbakk… - European Journal of …, 2021 - Elsevier
Lipid-based nanoparticles for RNA delivery (LNP-RNA) are revolutionizing the
nanomedicine field, with one approved gene therapy formulation and two approved …

[HTML][HTML] Quality assessment of LNP-RNA therapeutics with orthogonal analytical techniques

J Parot, D Mehn, H Jankevics, N Markova… - Journal of Controlled …, 2024 - Elsevier
The availability of analytical methods for the characterization of lipid nanoparticles (LNPs)
for in-vivo intracellular delivery of nucleic acids is critical for the fast development of …

[HTML][HTML] Field-flow fractionation-an excellent tool for fractionation, isolation and/or purification of biomacromolecules

SK Wiedmer, ML Riekkola - Journal of Chromatography A, 2023 - Elsevier
Field-flow fractionation (FFF) with its several variants, has developed into a mature
methodology. The scope of the FFF investigations has expanded, covering both a wide …