Age‐related macular degeneration (AMD) is a major cause of vision impairment in the
Western World, and with the aging world population, its incidence is increasing. As of today …

The most prevalent reason for vision impairment in aging inhabitants is age-related macular
degeneration (AMD), a posterior ocular disease with a poor understanding of the anatomic …

The precise molecular processes underlying the complement's activation, which follows
exposure to physical stress still remain to be fully elucidated. However, some possible …

Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis
worldwide and a frequent cause of kidney failure. Currently, the diagnosis necessitates a …

Complement is an ancient and complex network of the immune system and, as such, it plays
vital physiological roles, but it is also involved in numerous pathological processes. The …

Inherited retinal dystrophies (IRDs) as well as genetically complex retinal phenotypes
represent a heterogenous group of ocular diseases, both on account of their phenotypic and …

Ground-breaking awareness has been reached about the intricate and dynamic connection
between developing tumors and the host immune system. Being a powerful arm of innate …

Human complement is the first line of defence against invading pathogens and is involved in
tissue homeostasis. Complement-targeted therapies to treat several diseases caused by a …

Pseudomonas aeruginosa is a leading cause of nosocomial bloodstream infections. The
outcome of these infections depends on the virulence of the microorganism as well as host …

Background Secondary atypical hemolytic uremic syndrome (secondary aHUS) is a
heterogeneous group of thrombotic microangiopathies (TMA) associated with various …