Clinical and research updates on the VISTA immune checkpoint: immuno-oncology themes and highlights

RJ Noelle, JL Lines, LD Lewis, RE Martell… - Frontiers in …, 2023 - frontiersin.org
Immune checkpoints limit the activation of the immune system and serve an important
homeostatic function but can also restrict immune responses against tumors. Inhibition of …

Clinical landscape of macrophage-reprogramming cancer immunotherapies

JH Rannikko, M Hollmén - British Journal of Cancer, 2024 - nature.com
Tumour-associated macrophages (TAMs) sustain a tumour-supporting and
immunosuppressive milieu and therefore aggravate cancer prognosis. To modify TAM …