[HTML][HTML] Neural crest delamination and migration: from epithelium-to-mesenchyme transition to collective cell migration

E Theveneau, R Mayor - Developmental biology, 2012 - Elsevier
After induction and specification in the ectoderm, at the border of the neural plate, the neural
crest (NC) population leaves its original territory through a delamination process. Soon …

Mechanisms of neural crest migration

A Szabó, R Mayor - Annual Review of Genetics, 2018 - annualreviews.org
Neural crest cells are a transient embryonic cell population that migrate collectively to
various locations throughout the embryo to contribute a number of cell types to several …

ptk7 mutant zebrafish models of congenital and idiopathic scoliosis implicate dysregulated Wnt signalling in disease

M Hayes, X Gao, LX Yu, N Paria… - Nature …, 2014 - nature.com
Scoliosis is a complex genetic disorder of the musculoskeletal system, characterized by
three-dimensional rotation of the spine. Curvatures caused by malformed vertebrae …

Luminescence switch-on detection of protein tyrosine kinase-7 using a G-quadruplex-selective probe

S Lin, W Gao, Z Tian, C Yang, L Lu, JL Mergny… - Chemical …, 2015 - pubs.rsc.org
A series of luminescent iridium (III) complexes were synthesised and evaluated for their
ability to act as luminescent G-quadruplex-selective probes. The iridium (III) complex 9 [Ir …

Expression, regulation and targeting of receptor tyrosine kinases in esophageal squamous cell carcinoma

MK Kashyap, O Abdel-Rahman - Molecular cancer, 2018 - Springer
Esophageal cancer is one of the most common types of cancer, which is a leading cause of
cancer-related death worldwide. Based on histological behavior, it is mainly of two types (i) …

Neural crest migration: interplay between chemorepellents, chemoattractants, contact inhibition, epithelial–mesenchymal transition, and collective cell migration

E Theveneau, R Mayor - Wiley Interdisciplinary Reviews …, 2012 - Wiley Online Library
Neural crest (NC) cells are induced at the border of the neural plate and subsequently leave
the neuroepithelium during a delamination phase. This delamination involves either a …

The many roles of PTK7: a versatile regulator of cell–cell communication

H Peradziryi, NS Tolwinski, A Borchers - Archives of biochemistry and …, 2012 - Elsevier
PTK7 (protein tyrosine kinase 7) is an evolutionarily conserved transmembrane receptor
with functions in various processes ranging from embryonic morphogenesis to epidermal …

Metal complexes for the detection of disease-related protein biomarkers

DL Ma, M Wang, C Liu, X Miao, TS Kang… - Coordination chemistry …, 2016 - Elsevier
The detection of pathological biomarkers can allow for the early diagnosis and treatment of
human disease, lowering morbidity and improving quality of life. Transition metal complexes …

Anti-PTK7 monoclonal antibodies inhibit angiogenesis by suppressing PTK7 function

SW Oh, WS Shin, ST Lee - Cancers, 2022 - mdpi.com
Simple Summary PTK7 is a catalytically defective receptor protein tyrosine kinase. We
previously demonstrated that PTK7 enhances angiogenesis by interacting with KDR, a …

The biochemistry, signalling and disease relevance of RYK and other WNT-binding receptor tyrosine kinases

JP Roy, MM Halford, SA Stacker - Growth Factors, 2018 - Taylor & Francis
The receptor tyrosine kinases (RTKs) are a well-characterized family of growth factor
receptors that have central roles in human disease and are frequently therapeutically …