Severe disease during both primary and secondary dengue virus infections in pediatric populations

C Aggarwal, H Ahmed, P Sharma, ES Reddy… - Nature medicine, 2024 - nature.com
Dengue is a global epidemic causing over 100 million cases annually. The clinical
symptoms range from mild fever to severe hemorrhage and shock, including some fatalities …

Evolutionary dynamics of dengue virus in India

S Jagtap, C Pattabiraman, A Sankaradoss… - PLoS …, 2023 - journals.plos.org
More than a hundred thousand dengue cases are diagnosed in India annually, and about
half of the country's population carries dengue virus-specific antibodies. Dengue propagates …

[HTML][HTML] Genotype replacement of dengue virus type 3 and clade replacement of dengue virus type 2 genotype Cosmopolitan in Dhaka, Bangladesh in 2017

K Suzuki, J Phadungsombat, EE Nakayama… - Infection, Genetics and …, 2019 - Elsevier
Dengue is a mosquito-borne disease that has spread to> 100 countries and is caused by the
dengue virus (DENV), which belongs to the Flavivirus genus of the family Flaviviridae. DENV …

Nucleic acid quantification with amplicon yield in recombinase polymerase amplification

P Valloly, R Roy - Analytical Chemistry, 2022 - ACS Publications
Amplification-based quantitative polymerase chain reaction (qPCR) provides accurate and
sensitive nucleic acid quantification. However, the requirement of temperature cycling and …

Neutralizing antibodies from prior exposure to dengue virus negatively correlate with viremia on re-infection

A Anantharaj, T Agrawal, PK Shashi, A Tripathi… - Communications …, 2023 - nature.com
Background India is hyperendemic to dengue and over 50% of adults are seropositive.
There is limited information on the association between neutralizing antibody profiles from …

Immune profile and responses of a novel dengue DNA vaccine encoding an EDIII-NS1 consensus design based on Indo-African sequences

A Sankaradoss, S Jagtap, J Nazir, SE Moula, A Modak… - Molecular Therapy, 2022 - cell.com
The ongoing COVID-19 pandemic highlights the need to tackle viral variants, expand the
number of antigens, and assess diverse delivery systems for vaccines against emerging …

Detection of dengue virus type 2 of Indian origin in acute febrile patients in rural Kenya

MM Masika, EM Korhonen, T Smura… - PLoS neglected …, 2020 - journals.plos.org
Dengue virus (DENV) has caused recent outbreaks in coastal cities of Kenya, but the
epidemiological situation in other areas of Kenya is largely unknown. We investigated the …

[HTML][HTML] Genetic diversity and spatiotemporal dynamics of DENV-1 and DENV-2 infections during the 2012–2013 outbreak in Mexico

ED Rodríguez-Aguilar, J Martínez-Barnetche… - Virology, 2022 - Elsevier
Dengue fever is caused by four related dengue virus serotypes, DENV-1 to DENV-4, where
each serotype comprises distinct genotypes and lineages. The last major outbreak in Mexico …

Ultradiluted Eupatorium perfoliatum Alleviates DENV-induced Fibrosis By Regulation of TGFβ1, MMP-9 and Interferons

A Sarkar, A Roy, M Maity, D Nayak, S Das - Future Virology, 2023 - Taylor & Francis
Aim: This study aimed to alleviate dengue virus (DENV)-mediated fibrosis in a chick embryo
model using ultradiluted Eupatorium perfoliatum (UEP). Materials & methods …

Molecular characterization and phylogenetic analysis of the 2019 dengue outbreak in Wenzhou, China

A Han, B Sun, Z Sun, X Xu, Q Yang, D Xie… - Frontiers in Cellular …, 2022 - frontiersin.org
In 2019, a dengue outbreak occurred with 290 confirmed cases in Wenzhou, a coastal city in
southeast China. To identify the origin of the dengue virus (DENV) from this outbreak, viral …