By controlling the passage of small molecules across lipid bilayers, membrane transporters
influence not only the uptake and efflux of nutrients, but also the metabolic state of the cell …

Flavonoids are widely existing compounds with enormous pharmacological effects from food
and medicine. However, the low bioavailability in intestinal absorption and metabolism limits …

Organophosphate flame retardants (OPFRs) are environmental pollutants of increasing
interest, widely distributed in the environment and exerting possible deleterious effects …

Human membrane drug transporters are recognized as major actors of pharmacokinetics;
they also handle endogenous compounds, including hormones and metabolites. Chemical …

A defining feature of sea urchins is their extreme fecundity. Urchins produce millions of
transparent, synchronously developing embryos, ideal for spatial and temporal analysis of …

Abstract Micro-and nanoplastics (MPs/NPs) constitute emerging and widely-distributed
environmental contaminants to which humans are highly exposed. They possibly represent …

Environmental health science seeks to predict how environmental toxins, chemical toxicants,
and prescription drugs accumulate and interact within the body. Xenobiotic transporters of …

An organism's diet is a major route of exposure to both beneficial nutrients and toxic
environmental chemicals and natural products. The uptake of dietary xenobiotics in the …

The placenta is a temporary endocrine organ that facilitates gas, nutrient, and waste
exchange between maternal and fetal compartments, partially shielding the fetus from …

Succinate dehydrogenase inhibitors (SDHIs) are widely-used fungicides, to which humans
are exposed and for which putative health risks are of concern. In order to identify human …