Polymeric micelles for the delivery of poorly soluble drugs: From nanoformulation to clinical approval

D Hwang, JD Ramsey, AV Kabanov - Advanced drug delivery reviews, 2020 - Elsevier
Over the last three decades, polymeric micelles have emerged as a highly promising drug
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …

Nanocarriers for delivery of platinum anticancer drugs

HS Oberoi, NV Nukolova, AV Kabanov… - Advanced drug delivery …, 2013 - Elsevier
Platinum based anticancer drugs have revolutionized cancer chemotherapy, and continue to
be in widespread clinical use especially for management of tumors of the ovary, testes, and …

A Rationally Designed Bimetallic Platinum (II)‐Ferrocene Antitumor Agent Induces Non‐Apoptotic Cell Death and Exerts in Vivo Efficacy

S Gadre, M Manikandan, P Duari… - … A European Journal, 2022 - Wiley Online Library
Despite phenomenal clinical success, the efficacy of platinum anticancer drugs is often
compromised due to inherent and acquired drug resistant phenotypes in cancers. To …

Vinyl Polymer-based technologies towards the efficient delivery of chemotherapeutic drugs

P Pereira, AC Serra, JFJ Coelho - Progress in Polymer Science, 2021 - Elsevier
The application of synthetic polymers as delivery systems of chemotherapy drugs has
opened a very prospective field for research in cancer therapy. Due to their unique and …

A new approach to reduce toxicities and to improve bioavailabilities of platinum-containing anti-cancer nanodrugs

L Liu, Q Ye, M Lu, YC Lo, YH Hsu, MC Wei, YH Chen… - Scientific reports, 2015 - nature.com
Platinum (Pt) drugs are the most potent and commonly used anti-cancer chemotherapeutics.
Nanoformulation of Pt drugs has the potential to improve the delivery to tumors and reduce …

Polymeric micelles for targeted tumor therapy of platinum anticancer drugs

Y Mochida, H Cabral, K Kataoka - Expert Opinion on Drug Delivery, 2017 - Taylor & Francis
Introduction: Platinum anticancer drugs are effective against a wide range of tumors, though
their severe adverse effects and resistance remain unresolved. A breakthrough in these …

Exploiting developments in nanotechnology for the preferential delivery of platinum-based anti-cancer agents to tumours: targeting some of the hallmarks of cancer

JP Parker, Z Ude, CJ Marmion - Metallomics, 2016 - academic.oup.com
Platinum drugs as anti-cancer therapeutics are held in extremely high regard. Despite their
success, there are drawbacks associated with their use; their dose-limiting toxicity, their …

Poly(Ethylene Glycol)-b-Poly(D,L-Lactide) Nanoparticles as Potential Carriers for Anticancer Drug Oxaliplatin

YA Kadina, EV Razuvaeva, DR Streltsov, NG Sedush… - Molecules, 2021 - mdpi.com
Nanoparticles based on biocompatible methoxy poly (ethylene glycol)-b-poly (D, L-
lactide)(mPEG113-bP (D, L) LA n) copolymers as potential vehicles for the anticancer agent …

Bioinspired hyaluronic acid and polyarginine nanoparticles for DACHPt delivery

K Matha, G Lollo, G Taurino, R Respaud… - European Journal of …, 2020 - Elsevier
This work here presented provides insights over a novel biodegradable polymeric
nanosystem made of hyaluronic acid and polyarginine for diaminocyclohexane-platinum …

LHRH-targeted nanogels as a delivery system for cisplatin to ovarian cancer

NV Nukolova, HS Oberoi, Y Zhao… - Molecular …, 2013 - ACS Publications
Targeted drug delivery using multifunctional polymeric nanocarriers is a modern approach
for cancer therapy. Our purpose was to prepare targeted nanogels for selective delivery of …