Alpha-lipoic acid: An antioxidant with anti-aging properties for disease therapy

M Shanaida, R Lysiuk, O Mykhailenko… - Current Medicinal …, 2025 - benthamdirect.com
The anti-aging effects of alpha-lipoic acid (αLA), a natural antioxidant synthesized in human
tissues, have attracted a growing interest in recent years. αLA is a short-chain sulfur …

In Vitro Evaluation of the Antiamoebic Activity of Kaempferol against Trophozoites of Entamoeba histolytica and in the Interactions of Amoebae with Hamster …

D Levaro-Loquio, J Serrano-Luna… - International Journal of …, 2023 - mdpi.com
Entamoeba histolytica (E. histolytica) is a parasite in humans that provokes amoebiasis. The
most employed drug is metronidazole (MTZ); however, some studies have reported that this …

Effects of α-lipoic acid on growth performance, antioxidant capacity, and immune function in sheep

X Yang, H Zhang, F Pang, L Zhang, T Fu… - Journal of animal …, 2023 - academic.oup.com
Abstract α-Lipoic acid (α-LA) was usually applied to improve the ability of removing the
reactive oxygen species of host. The affection of α-LA on ruminants was mainly focused on …

Anticancer effects of alpha-lipoic acid, a potent organosulfur compound by modulating matrix metalloproteinases and apoptotic markers in osteosarcoma MG-63 cells

A Ahmadi, F Hosseini, M Rostami… - The Journal of Steroid …, 2024 - Elsevier
Osteosarcoma (OS), an extremely aggressive form of bone tumor primarily affects young
adults. Despite significant advancements in clinical trials, the ability of cancer cells to …

[HTML][HTML] Effects of Yinzhihuang on alleviating cyclosporine A-induced cholestatic liver injury via farnesoid X receptor-mediated regulation of transporters and enzymes …

Y Qin, J Tan, X Han, N Wang, X Zhai… - Biological and …, 2023 - jstage.jst.go.jp
Yinzhihuang (YZH), a traditional Chinese medicine prescription, was widely used to treat
cholestasis. Cholestatic liver injury limited the use of the immunosuppressive drug …

Protective effect of alpha‑lipoic acid against in utero cytarabine exposure-induced hepatotoxicity in rat female neonates

R Namoju, KN Chilaka - Naunyn-Schmiedeberg's Archives of …, 2024 - Springer
Cytarabine, an anti-metabolite drug, remains the mainstay of treatment for hematological
malignancies. It causes various toxic effects including teratogenicity. Alpha lipoic acid (ALA) …

Biased Quantification of Rat Liver Fibrosis—Meta-Analysis with Practical Recommendations and Clinical Implications

P Mik, K Barannikava, P Surkova - Journal of Clinical Medicine, 2023 - mdpi.com
For liver fibrosis assessment, the liver biopsy is usually stained with Masson's trichrome (MT)
or picrosirius red (PSR) to quantify liver connective tissue (LCT) for fibrosis scoring …

Combination of flaxseed and clarified tomato juice in bread: Delayed effect on metabolic disorders during long-term unbalanced diet in an in vivo experiment

IM Zharkova, AV Grebenshchikov… - Nutrition and …, 2024 - journals.sagepub.com
Objective The objective of study was to evaluate the biological effects occurring in the
animal body in conditions of a regular consumption of bread with a combination of flaxseed …

[PDF][PDF] Efficacy of Resatorvid and Alpha-Lipoic Acid in Ameliorating Gentamicin-Induced Liver Injury: Insights from Rat Model Study

D Hatipoglu, MB Ates, A Bulut, B Gezgic… - Pakistan Veterinary …, 2024 - pvj.com.pk
The aim of our study was to investigate the potential effects of alpha-lipoic acid (ALA) and
resatorvid (RES) on gentamicin-induced hepatotoxicity. Thirty-four rats were divided into the …

Hepatoprotective effect of flaxseed oil and alpha lipoic acid against cisplatin-induced oxidative stress and apoptosis in rats

A Alsoudany, E Salah… - Benha Veterinary Medical …, 2023 - bvmj.journals.ekb.eg
Cisplatin (CP) is a widely used chemotherapy agent. The study's goal was to assess the
antioxidant and antiapoptoptic effects of flaxseed oil (FXO) and/or alpha lipoic acid (ALA) …