The origin and evolution of cell types

D Arendt, JM Musser, CVH Baker, A Bergman… - Nature Reviews …, 2016 - nature.com
Cell types are the basic building blocks of multicellular organisms and are extensively
diversified in animals. Despite recent advances in characterizing cell types, classification …

The origin of animal multicellularity and cell differentiation

T Brunet, N King - Developmental cell, 2017 - cell.com
Over 600 million years ago, animals evolved from a unicellular or colonial organism whose
cell (s) captured bacteria with a collar complex, a flagellum surrounded by a microvillar …

The origin of Metazoa: a unicellular perspective

A Sebé-Pedrós, BM Degnan, I Ruiz-Trillo - Nature Reviews Genetics, 2017 - nature.com
The first animals evolved from an unknown single-celled ancestor in the Precambrian
period. Recently, the identification and characterization of the genomic and cellular traits of …

Profiling cellular diversity in sponges informs animal cell type and nervous system evolution

JM Musser, KJ Schippers, M Nickel, G Mizzon… - Science, 2021 - science.org
The evolutionary origin of metazoan cell types such as neurons and muscles is not known.
Using whole-body single-cell RNA sequencing in a sponge, an animal without nervous …

From nerve net to nerve ring, nerve cord and brain—evolution of the nervous system

D Arendt, MA Tosches, H Marlow - Nature Reviews Neuroscience, 2016 - nature.com
The puzzle of how complex nervous systems emerged remains unsolved. Comparative
studies of neurodevelopment in cnidarians and bilaterians suggest that this process began …

Light-regulated collective contractility in a multicellular choanoflagellate

T Brunet, BT Larson, TA Linden, MJA Vermeij… - Science, 2019 - science.org
Collective cell contractions that generate global tissue deformations are a signature feature
of animal movement and morphogenesis. However, the origin of collective contractility in …

Pluripotency and the origin of animal multicellularity

S Sogabe, WL Hatleberg, KM Kocot, TE Say, D Stoupin… - Nature, 2019 - nature.com
A widely held—but rarely tested—hypothesis for the origin of animals is that they evolved
from a unicellular ancestor, with an apical cilium surrounded by a microvillar collar, that …

Alternative neural systems: what is a neuron?(ctenophores, sponges and placozoans)

LL Moroz, DY Romanova - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
How to make a neuron, a synapse, and a neural circuit? Is there only one 'design'for a
neural architecture with a universally shared genomic blueprint across species? The brief …

[HTML][HTML] Evolution of neuronal types and families

D Arendt, PY Bertucci, K Achim, JM Musser - Current opinion in …, 2019 - Elsevier
Highlights•Solving nervous system evolution requires cross-species comparison of neuronal
types.•Neuronal types are commonly defined by their specific structure and function.•We …

High cell diversity and complex peptidergic signaling underlie placozoan behavior

F Varoqueaux, EA Williams, S Grandemange… - Current Biology, 2018 - cell.com
Placozoans, together with sponges, are the only animals devoid of a nervous system and
muscles, yet both respond to sensory stimulation in a coordinated manner. How behavioral …