The neuroprotective effects of intermittent fasting on brain aging and neurodegenerative diseases via regulating mitochondrial function

Y Zhao, M Jia, W Chen, Z Liu - Free Radical Biology and Medicine, 2022 - Elsevier
Intermittent fasting (IF) has been studied for its effects on lifespan and the prevention or
delay of age-related diseases upon the regulation of metabolic pathways. Mitochondria …

Mitochondrial dysfunction is a common denominator linking skeletal muscle wasting due to disease, aging, and prolonged inactivity

HW Hyatt, SK Powers - Antioxidants, 2021 - mdpi.com
Skeletal muscle is the most abundant tissue in the body and is required for numerous vital
functions, including breathing and locomotion. Notably, deterioration of skeletal muscle …

Ultrastructural features mirror metabolic derangement in human endothelial cells exposed to high glucose

R Scrimieri, L Locatelli, A Cazzaniga, R Cazzola… - Scientific reports, 2023 - nature.com
High glucose-induced endothelial dysfunction is the early event that initiates diabetes-
induced vascular disease. Here we employed Cryo Soft X-ray Tomography to obtain three …

Aerobic exercise and resistance exercise alleviate skeletal muscle atrophy through IGF-1/IGF-1R-PI3K/Akt pathway in mice with myocardial infarction

L Feng, B Li, Y Xi, M Cai, Z Tian - American Journal of …, 2022 - journals.physiology.org
Myocardial infarction (MI)-induced heart failure (HF) is commonly accompanied with
profound effects on skeletal muscle. With the process of MI-induced HF, perturbations in …

Microalgae produce antioxidant molecules with potential preventive effects on mitochondrial functions and skeletal muscular oxidative stress

J Vignaud, C Loiseau, J Hérault, C Mayer, M Côme… - Antioxidants, 2023 - mdpi.com
In recent years, microalgae have become a source of molecules for a healthy life. Their
composition of carbohydrates, peptides, lipids, vitamins and carotenoids makes them a …

The role of mitophagy in skeletal muscle damage and regeneration

E Chatzinikita, M Maridaki, K Palikaras, M Koutsilieris… - Cells, 2023 - mdpi.com
Mitochondria are cellular organelles that play an essential role in generating the chemical
energy needed for the biochemical reactions in cells. Mitochondrial biogenesis, ie, de novo …

Adenosine monophosphate activated protein kinase contributes to skeletal muscle health through the control of mitochondrial function

Y Yan, M Li, J Lin, Y Ji, K Wang, D Yan… - Frontiers in …, 2022 - frontiersin.org
Skeletal muscle is one of the largest organs in the body and the largest protein repository.
Mitochondria are the main energy-producing organelles in cells and play an important role …

Muscle aging and sarcopenia: The pathology, etiology, and most promising therapeutic targets

M Grima-Terrén, S Campanario… - Molecular Aspects of …, 2024 - Elsevier
Sarcopenia is a progressive muscle wasting disorder that severely impacts the quality of life
of elderly individuals. Although the natural aging process primarily causes sarcopenia, it can …

Mitochondrial network remodeling: an important feature of myogenesis and skeletal muscle regeneration

FA Rahman, J Quadrilatero - Cellular and Molecular Life Sciences, 2021 - Springer
The remodeling of the mitochondrial network is a critical process in maintaining cellular
homeostasis and is intimately related to mitochondrial function. The interplay between the …

Sepsis induces muscle atrophy by inhibiting proliferation and promoting apoptosis via PLK1‐AKT signalling

YY Cao, Z Wang, T Yu, Y Zhang… - Journal of Cellular …, 2021 - Wiley Online Library
Sepsis and sepsis‐induced skeletal muscle atrophy are common in patients in intensive
care units with high mortality, while the mechanisms are controversial and complicated. In …