G6PDH as a key immunometabolic and redox trigger in arthropods

B Moraes, R Martins, C Lopes, R Martins… - Frontiers in …, 2023 - frontiersin.org
The enzyme glucose-6-phosphate dehydrogenase (G6PDH) plays crucial roles in glucose
homeostasis and the pentose phosphate pathway (PPP), being also involved in redox …

Comprehensive review on glucose 6 phosphate dehydrogenase: A critical immunometabolic and redox switch in insects

MU Ghani, Z Yang, T Feng, J Chen, Z Khosravi… - International Journal of …, 2024 - Elsevier
Mounting an active immune response is energy intensive and demands the reallocation of
nutrients to maintain the body's resistance and tolerance against infections. Central to this …

Hemoglobin S and glucose-6-phosphate dehydrogenase deficiency coinheritance in AS and SS individuals in malaria-endemic region: a study in Calabar, Nigeria

IM Okafor, HU Okoroiwu, CA Ekechi - Journal of Global Infectious …, 2019 - journals.lww.com
Background: Malaria placed a huge burden on human life and has been reported to be a
key health problem affecting developing countries. This study was designed to assay for …

Prevalence of G6PD deficiency and distribution of its genetic variants among malaria-suspected patients visiting Metehara health centre, Eastern Ethiopia

TT Shenkutie, D Nega, A Hailu, D Kepple… - Malaria Journal, 2022 - Springer
Abstract Background Glucose-6-phosphate dehydrogenase (G6PD) is cytosolic enzyme,
which has a vital role for the integrity and functioning of red blood cells. Lower activity of this …

[HTML][HTML] Molecular Characterization of Erythrocyte Glucose-6-Phosphate Dehydrogenase Deficiency in Different Ethnic Groups of Blood Donors in Mauritania

M Taleb, M Bakour, AT Brahim, SM Ghaber… - Frontiers in Bioscience …, 2023 - imrpress.com
Background: Glucose-6-phosphate-dehydrogenase (G6PD) deficiency is the most frequent
enzymopathy worldwide; it is a genetic disorder that affects red blood cells and causes …

Genetic Background of the Sickle Cell Disease Pediatric Population of Dakar, Senegal, and Characterization of a Novel Frameshift β-Thalassemia Mutation [HBB: c …

F Gueye Tall, C Martin, EH Malick Ndour, I Déme Ly… - …, 2017 - Taylor & Francis
Sickle cell disease is a genetic disorder with a large variability in the pattern and severity of
clinical manifestations. Different genetic modulators have been identified but very few …

Single low-dose primaquine for blocking transmission of Plasmodium falciparum malaria – a proposed model-derived age-based regimen for sub-Saharan Africa

WR Taylor, HK Naw, K Maitland, TN Williams… - BMC medicine, 2018 - Springer
Abstract Background In 2012, the World Health Organization recommended blocking the
transmission of Plasmodium falciparum with single low-dose primaquine (SLDPQ, target …

[HTML][HTML] G6PD Deficiency and COVID-19 in Burkina Faso: a possible link?

AK Ouattara, L Traoré, TR Compaoré… - Journal of Biosciences …, 2023 - scirp.org
Burkina Faso is a malaria-endemic country, with a high incidence of G6PD deficiency
(G6PDd), which recorded its first case of COVID-19 in March 2020. G6PDd leads to a …

[HTML][HTML] Fine mapping of glucose 6 phosphate dehydrogenase (G6PD) deficiency in a rural malaria area of south west Odisha using the clinical, hematological and …

R Kumar, MPSS Singh, S Mahapatra… - … of Hematology and …, 2020 - ncbi.nlm.nih.gov
Methods Diagnosis of G6PD deficiency was made by using the Di-chloroindophenol Dye
test in two south west districts (Kalahandi and Rayagada) of Odisha State. Demographic and …

Prevalence, genetic variants and clinical implications of G-6-PD deficiency in Burkina Faso: a systematic review

AK Ouattara, P Yameogo, L Traore, B Diarra… - BMC Medical …, 2017 - Springer
Background It is now well-known that some antimalarials such as primaquine may induce
severe hemolytic anemia in people with G-6-PD deficiency. Antimalarial drug prescriptions …