In a striking display of trans-kingdom symbiosis, gut bacteria cooperate with their animal hosts to regulate the development and function of the immune, metabolic and nervous …
Parkinson's disease (PD) may start in the gut and spread to the brain. To investigate the role of gut microbiome, we conducted a large-scale study, at high taxonomic resolution, using …
Gut microbiota represents a diverse and dynamic population of microorganisms harboring the gastrointestinal tract, which influences the host health and disease. Gut microbiota …
X Dong-Chen, C Yong, X Yang, ST Chen-Yu… - Signal transduction and …, 2023 - nature.com
Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide, and its treatment remains a big challenge. The pathogenesis of PD may be …
Mounting evidence suggests that the gut microbiome impacts brain development and function. Gut–brain connections may be mediated by an assortment of microbial molecules …
C Soto, S Pritzkow - Nature neuroscience, 2018 - nature.com
A hallmark event in neurodegenerative diseases (NDs) is the misfolding, aggregation, and accumulation of proteins, leading to cellular dysfunction, loss of synaptic connections, and …
K Kowalski, A Mulak - Journal of neurogastroenterology and …, 2019 - ncbi.nlm.nih.gov
Disturbances along the brain-gut-microbiota axis may significantly contribute to the pathogenesis of neurodegenerative disorders. Alzheimer's disease (AD) is the most frequent …
A Parker, S Fonseca, SR Carding - Gut microbes, 2020 - Taylor & Francis
The human gastrointestinal (gut) microbiota comprises diverse and dynamic populations of bacteria, archaea, viruses, fungi, and protozoa, coexisting in a mutualistic relationship with …
Amyloids are a class of protein with unique self-aggregation properties, and their aberrant accumulation can lead to cellular dysfunctions associated with neurodegenerative diseases …