Novel Bis-thiazoles with pyridine and 1, 4-Dihydropyridine linkers as potential anti-Alzheimer agents

MA Said, SM Riyadh, NS Al-Kaff, MEA Zaki… - Journal of Molecular …, 2025 - Elsevier
A series of bis-hydrazonothiazoles with pyridine and 1, 4-dihydropyridine linkers was
synthesized using 2, 2′-[(2, 6-dimethyl-1, 4-dihydropyridine-3, 5-diyl) bis (ethan-1-yl-1 …

Investigating the efficacy of naphthalene-thiazole hybrid hydrazones as α-glucosidase inhibitors

JY Al-Humaidi, AS Abouzied, MEA Zaki… - Journal of Molecular …, 2025 - Elsevier
In this study, a series of hydrazone derivatives containing naphthalene and thiazole hybrids
were synthesized through the condensation of (E)-4-methyl-2-(2-(naphthalen-1 …

Azole Derivatives: Cutting‐Edge Agents in Cancer Therapy

A Mehra, A Mittal, R Sangwan - ChemistrySelect, 2024 - Wiley Online Library
Monocyclic 5‐membered heterocycles including imidazoles, thiazoles, oxazoles, and their
related compounds have gained significant attention in medicinal chemistry because of their …

In silico prediction of some pharmacokinetic, safety, biological activity and molecular docking studies of 1-piperazine indole hybrid with nicotinic amide and nicotinic …

ML Mitku, AD Dagnaw, DT Geremew… - SAGE Open …, 2024 - journals.sagepub.com
Background: In silico predictions are now being utilized in drug discovery and design to
assess the physicochemical, pharmacokinetics, and safety properties of compounds at the …

[HTML][HTML] Synthesis, molecular docking, in silico study, and evaluation of bis-thiazole-based curcumin derivatives as potential antimicrobial agents

SM Gomha, AAAA El-Sayed, A Alrehaily… - Results in …, 2024 - Elsevier
The escalating challenge of antibiotic resistance, responsible for nearly a fifth of global
fatalities, underscores the critical need for innovative therapeutic approaches and the …