DAVID is a popular bioinformatics resource system including a web server and web service
for functional annotation and enrichment analyses of gene lists. It consists of a …

The hypothalamic arcuate–median eminence complex (Arc-ME) controls energy balance,
fertility and growth through molecularly distinct cell types, many of which remain unknown …

INTRODUCTION Transcription factors (TFs) are often studied one by one or in clusters of a
few related factors. However, the integration and networks of transcriptional changes to …

Neuroinflammation and microglial activation are significant processes in Alzheimer's
disease pathology. Recent genome-wide association studies have highlighted multiple …

Plants have adapted to tolerate and survive constantly changing environmental conditions
by reprogramming gene expression The dynamics of the contribution of alternative splicing …

Pathogenic COPA variants cause a Mendelian syndrome of immune dysregulation with
elevated type I interferon signaling. COPA is a subunit of coat protein complex I (COPI) that …

Skeletal muscle and brown adipose tissue (BAT) are functionally linked, as exercise
increases browning via secretion of myokines. It is unknown whether BAT affects muscle …

Protein S-palmitoylation is a reversible post-translational modification that regulates many
key biological processes, although the full extent and functions of protein S-palmitoylation …

Physical performance relies on the concerted action of myriad responses, many of which are
under circadian clock control. Little is known, however, regarding the time-dependent effect …

Proteostasis collapse, the diminished ability to maintain protein homeostasis, has been
established as a hallmark of nematode aging. However, whether proteostasis collapse …