The United States has long made substantial investments in clinical research with the goal
of improving the health and well-being of our nation. There is no doubt that these …

Heart failure is a significant public health burden that differentially impacts women. Important
sex-and gender-based differences in HF risk factors, presentation, and treatment exist, and …

Importance Despite bearing a disproportionate burden of heart failure (HF), Black and
Hispanic individuals have been poorly represented in HF clinical trials. Underrepresentation …

Purpose: Cardiac rehabilitation (CR) has been shown to improve functional status, quality of
life, and recurrent cardiovascular disease (CVD) events. Despite its demonstrated …

The aim of this study was to evaluate whether there were significant sex x time interactions
in lipoprotein (a)(Lp (a)) and low-density lipoprotein cholesterol (LDL-C) response to …

Cardiovascular disease (CVD) is the leading cause of death in women, with
underrepresented minority (URM) women experiencing the highest mortality rate. For …

Background & Aims Observational studies have linked lipid-lowering drug targets pro-
protein convertase subtilisin/kexin 9 (PCSK9) and HMG-CoA reductase (HMGCR) with …

Background Significant race and sex disparities exist in the prevalence, diagnosis, and
outcomes of peripheral artery disease (PAD). However, clinical trials evaluating treatments …

Mid-life, the years leading up to and following the menopause transition, in women is
accompanied by a change in cardiometabolic risk factors, including increases in body …

Importance Socioeconomically disadvantaged patients, such as persons with low income
and those with low educational attainment, are less likely to participate in clinical trials than …