Inappropriate activation of the renin-angiotensin system (RAS) exacerbates renal and
vascular injury. Accordingly, treatment with global RAS antagonists attenuates …

Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disorder that
predominantly affects women during their reproductive years. Although SLE can affect any …

Studies in humans and animal models indicate a key contribution of angiotensin II to the
pathogenesis of glomerular diseases. To examine the role of type 1 angiotensin (AT1) …

The angiotensin converting enzyme (ACE) I/D polymorphism has been one of the most
studied genetic systems. It comprises hundreds of reports and a myriad of disease …

Angiotensin II is a strong candidate for the perpetuation of autoimmunity, nephritis and
visceral damage in systemic lupus erythematosus (SLE). Our goal was to determine whether …

Inflammation and immune system dysfunction contributes to the development of
cardiovascular and renal disease. Systemic lupus erythematosus (SLE) is a chronic …

Objective. Results from studies of the association between angiotensin-converting enzyme
(ACE) insertion/deletion (I/D) gene polymorphism and systemic lupus erythematosus …

Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterized by
the production of autoantibodies and the development of immune complex …

An apparent low prevalence of cancer in hypertensive patients receiving angiotensin
converting enzyme inhibitors is reported; however, the molecular mechanisms have not …

The relation between sarcoidosis and autoimmune disorders was first suggested by Telium
about half a century ago. He noted that there were certain clinical and laboratory similarities …