GABA tone regulation and its cognitive functions in the brain
Abstract γ-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter released at
GABAergic synapses, mediating fast-acting phasic inhibition. Emerging lines of evidence …
GABAergic synapses, mediating fast-acting phasic inhibition. Emerging lines of evidence …
GAD antibodies in neurological disorders—insights and challenges
F Graus, A Saiz, J Dalmau - Nature Reviews Neurology, 2020 - nature.com
Antibodies to glutamic acid decarboxylase (GAD) have been associated with several
neurological syndromes, including stiff-person syndrome, cerebellar ataxia and epilepsy …
neurological syndromes, including stiff-person syndrome, cerebellar ataxia and epilepsy …
Two genes encode distinct glutamate decarboxylases
MG Erlander, NJK Tillakaratne, S Feldblum, N Patel… - Neuron, 1991 - cell.com
Summary y-Aminobutyric acid (CABA) is the most widely distributed known inhibitory
neurotransmitter in the vertebrate brain. GABA also serves regulatory and trophic roles in …
neurotransmitter in the vertebrate brain. GABA also serves regulatory and trophic roles in …
GABAergic interneurons: implications for understanding schizophrenia and bipolar disorder
FM Benes, S Berretta - Neuropsychopharmacology, 2001 - Elsevier
A core component to corticolimbic circuitry is the GABAergic interneuron. Neuroanatomic
studies conducted over the past century have demonstrated several subtypes of interneuron …
studies conducted over the past century have demonstrated several subtypes of interneuron …
Local GABA circuit control of experience-dependent plasticity in developing visual cortex
Sensory experience in early life shapes the mammalian brain. An impairment in the activity-
dependent refinement of functional connections within developing visual cortex was …
dependent refinement of functional connections within developing visual cortex was …
GABA and GABA receptors in the central nervous system and other organs
M Watanabe, K Maemura, K Kanbara… - International review of …, 2002 - Elsevier
γ-Aminobutyrate (GABA) is a major inhibitory neurotransmitter in the adult mammalian brain.
GABA is also considered to be a multifunctional molecule that has different situational …
GABA is also considered to be a multifunctional molecule that has different situational …
Striatal interneurones: chemical, physiological and morphological characterization
The neostriatum is the larges* component of the basal ganglia, and the main recipient of
afferents to the basal ganglia from the cerebral cortex and thalamus. Studies of the cellular …
afferents to the basal ganglia from the cerebral cortex and thalamus. Studies of the cellular …
Towards a better understanding of GABAergic remodeling in Alzheimer's disease
K Govindpani, B Calvo-Flores Guzmán… - International journal of …, 2017 - mdpi.com
γ-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the vertebrate brain.
In the past, there has been a major research drive focused on the dysfunction of the …
In the past, there has been a major research drive focused on the dysfunction of the …
Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord
KA Moore, T Kohno, LA Karchewski… - Journal of …, 2002 - Soc Neuroscience
To clarify whether inhibitory transmission in the superficial dorsal horn of the spinal cord is
reduced after peripheral nerve injury, we have studied synaptic transmission in lamina II …
reduced after peripheral nerve injury, we have studied synaptic transmission in lamina II …
Two isoforms of glutamate decarboxylase: why?
JJ Soghomonian, DL Martin - Trends in pharmacological sciences, 1998 - cell.com
Adults express two isoforms of glutamate decarboxylase (GAD), GAD67 and GAD65, which
are encoded by different independently regulated genes, a situation that differs from that of …
are encoded by different independently regulated genes, a situation that differs from that of …