[HTML][HTML] Insulin/insulin-like growth factor signaling in C. elegans

CT Murphy, PJ Hu - WormBook: The Online Review of C. elegans …, 2018 - ncbi.nlm.nih.gov
The C. elegans insulin/IGF-1 signaling (IIS) pathway connects nutrient levels to metabolism,
growth, development, longevity, and behavior. This fundamental pathway is regulated by …

TCF/LEFs and Wnt signaling in the nucleus

KM Cadigan, ML Waterman - Cold Spring Harbor …, 2012 - cshperspectives.cshlp.org
T-cell factor/lymphoid enhancer factor (TCF/LEF) transcription factors are the major end
point mediators of Wnt/Wingless signaling throughout metazoans. TCF/LEFs are …

Asymmetric and symmetric stem-cell divisions in development and cancer

SJ Morrison, J Kimble - nature, 2006 - nature.com
Listen to an interview with Sean Morrison on the stem cells podcast Much has been made of
the idea that asymmetric cell division is a defining characteristic of stem cells that enables …

The FRIGIDA Complex Activates Transcription of FLC, a Strong Flowering Repressor in Arabidopsis, by Recruiting Chromatin Modification Factors

K Choi, J Kim, HJ Hwang, S Kim, C Park, SY Kim… - The Plant …, 2011 - academic.oup.com
The flowering of Arabidopsis thaliana winter annuals is delayed until the subsequent spring
by the strong floral repressor FLOWERING LOCUS C (FLC). FRIGIDA (FRI) activates the …

Wnt signaling: complexity at the surface

KM Cadigan, YI Liu - Journal of cell science, 2006 - journals.biologists.com
Wnts are secreted proteins that are essential for a wide array of developmental and
physiological processes. They signal across the plasma membrane by interacting with …

Smed-βcatenin-1 Is Required for Anteroposterior Blastema Polarity in Planarian Regeneration

CP Petersen, PW Reddien - Science, 2008 - science.org
Planarian flatworms can regenerate heads at anterior-facing wounds and tails at posterior-
facing wounds throughout the body. How this regeneration polarity is specified has been a …

Armadillo-repeat protein functions: questions for little creatures

R Tewari, E Bailes, KA Bunting, JC Coates - Trends in cell biology, 2010 - cell.com
Armadillo (ARM)-repeat proteins form a large family with diverse and fundamental functions
in many eukaryotes. ARM-repeat proteins have largely been characterised in multicellular …

Controls of Germline Stem Cells, Entry into Meiosis, and the Sperm/Oocyte Decision in Caenorhabditis elegans

J Kimble, SL Crittenden - Annu. Rev. Cell Dev. Biol., 2007 - annualreviews.org
The Caenorhabditis elegans germ line provides an exceptional model for analysis of the
molecular controls governing stem cell maintenance, the cell cycle transition from mitosis to …

Mechanistic insights from structural studies of β-catenin and its binding partners

W Xu, D Kimelman - Journal of cell science, 2007 - journals.biologists.com
β-catenin is both a crucial regulator of cell adhesion and the central effector of the canonical
Wnt signaling pathway. It functions as a protein organizer by interacting with numerous …

What does the concept of the stem cell niche really mean today?

AD Lander, J Kimble, H Clevers, E Fuchs, D Montarras… - BMC biology, 2012 - Springer
© 2012 Lander et al; licensee BioMed Central Ltd. This is an Open Access article distributed
under the terms of the Creative Commons Attribution License (http://creativecommons …