A novel multiple hypothesis based particle tracking method for clathrin mediated endocytosis analysis using fluorescence microscopy

L Liang, H Shen, P De Camilli… - IEEE transactions on …, 2014 - ieeexplore.ieee.org
In order to quantitatively analyze biological images and study underlying mechanisms of the
cellular and subcellular processes, it is often required to track a large number of particles …

Shape component analysis: structure-preserving dimension reduction on biological shape spaces

HC Lee, T Liao, YJ Zhang, G Yang - Bioinformatics, 2016 - academic.oup.com
Motivation: Quantitative shape analysis is required by a wide range of biological studies
across diverse scales, ranging from molecules to cells and organisms. In particular, high …

Integrating dimension reduction with mean-shift clustering for biological shape classification

HC Lee, G Yang - 2014 IEEE 11th International Symposium on …, 2014 - ieeexplore.ieee.org
Quantitative shape analysis is required in a broad range of biological studies. Mean-shift
clustering provides a powerful approach for automated biological shape classification …

Computational removal ofbackground fluorescence for biological fluorescence microscopy

HC Lee, G Yang - 2014 IEEE 11th International Symposium on …, 2014 - ieeexplore.ieee.org
Background fluorescence is a frequently encountered problem in biological fluorescence
microscopy. It often significantly lowers the image signal-to-noise ratio and poses substantial …

Axonal transport velocity estimation from kymographs based on curvilinear feature extraction and spline fitting

A Nair, S Ramanarayanan, S Ahlawat… - 2014 36th Annual …, 2014 - ieeexplore.ieee.org
Axonal transport velocities are obtained from spatio-temporal maps called kymographs
developed from time-lapse confocal microscopy movies of neurons. The kymographs of …

Computational Image Modeling for Characterization and Analysis of Intracellular Cargo Transport

KC Chen, M Qiu, J Kovacevic, G Yang - … , PA, USA, September 3-5, 2014 4, 2014 - Springer
Active intracellular cargo transport is essential to survival and function of eukaryotic cells.
How this process is controlled spatially and temporally so that the right cargo is delivered to …

Image-based computational tracking and analysis of spindle protein dynamics

G Yang - Mitosis: Methods and Protocols, 2014 - Springer
The spindle is a highly complex and dynamic molecular machine that is assembled during
cell division for accurate segregation of replicated chromosomes. Successful completion of …

Image-based representation and modeling of spatiotemporal cell dynamics

G Yang, JC Olivo-Marin - 2013 IEEE 10th International …, 2013 - ieeexplore.ieee.org
Successful completion of dynamic cellular processes ranging from intracellular transport to
embryonic development depends critically on precise spatial and temporal coordination of …

Image-based measurement of cargo traffic flow in complex neurite networks

X Chai, D Qian, Q Ba, A Li, YJ Zhang… - 2017 IEEE International …, 2017 - ieeexplore.ieee.org
Neurons depend critically on active transport of cargoes throughout their complex neurite
networks for their survival and function. Defects in this process have been strongly …

[PDF][PDF] Automated analysis of kymograph images for quantitative study of ciliary transport

S Chakraburty - 2016 - getd.libs.uga.edu
Intraflagellar transport (IFT) is essential for the construction of cilia and flagella in eukaryotic
cells and plays a critical role in the transport of protein cargo to and from the cell body …