The emergence of adaptive laboratory evolution as an efficient tool for biological discovery and industrial biotechnology
Harnessing the process of natural selection to obtain and understand new microbial
phenotypes has become increasingly possible due to advances in culturing techniques …
phenotypes has become increasingly possible due to advances in culturing techniques …
Adaptive laboratory evolution–principles and applications for biotechnology
M Dragosits, D Mattanovich - Microbial cell factories, 2013 - Springer
Adaptive laboratory evolution is a frequent method in biological studies to gain insights into
the basic mechanisms of molecular evolution and adaptive changes that accumulate in …
the basic mechanisms of molecular evolution and adaptive changes that accumulate in …
Evolution experiments with microorganisms: the dynamics and genetic bases of adaptation
Microorganisms have been mutating and evolving on Earth for billions of years. Now, a field
of research has developed around the idea of using microorganisms to study evolution in …
of research has developed around the idea of using microorganisms to study evolution in …
Tuning gene expression to changing environments: from rapid responses to evolutionary adaptation
Organisms are constantly exposed to a wide range of environmental changes, including
both short-term changes during their lifetime and longer-term changes across generations …
both short-term changes during their lifetime and longer-term changes across generations …
Acetate as a potential feedstock for the production of value-added chemicals: metabolism and applications
Acetate is regarded as a promising carbon feedstock in biological production owing to its
possible derivation from C 1 gases such as CO, CO 2 and methane. To best use of acetate …
possible derivation from C 1 gases such as CO, CO 2 and methane. To best use of acetate …
Evolutionary rescue and the limits of adaptation
G Bell - Philosophical Transactions of the Royal Society …, 2013 - royalsocietypublishing.org
Populations subject to severe stress may be rescued by natural selection, but its operation is
restricted by ecological and genetic constraints. The cost of natural selection expresses the …
restricted by ecological and genetic constraints. The cost of natural selection expresses the …
An adaptive biomolecular condensation response is conserved across environmentally divergent species
S Keyport Kik, D Christopher, H Glauninger… - Nature …, 2024 - nature.com
Cells must sense and respond to sudden maladaptive environmental changes—stresses—
to survive and thrive. Across eukaryotes, stresses such as heat shock trigger conserved …
to survive and thrive. Across eukaryotes, stresses such as heat shock trigger conserved …
Trade-offs in thermal adaptation: the need for a molecular to ecological integration
HO Pörtner, AF Bennett, F Bozinovic… - Physiological and …, 2006 - journals.uchicago.edu
Through functional analyses, integrative physiology is able to link molecular biology with
ecology as well as evolutionary biology and is thereby expected to provide access to the …
ecology as well as evolutionary biology and is thereby expected to provide access to the …
Genomic Islands and the Ecology and Evolution of Prochlorococcus
Prochlorococcus ecotypes are a useful system for exploring the origin and function of
diversity among closely related microbes. The genetic variability between phenotypically …
diversity among closely related microbes. The genetic variability between phenotypically …
Parallel adaptive evolution cultures of Escherichia coli lead to convergent growth phenotypes with different gene expression states
SS Fong, AR Joyce, BØ Palsson - Genome research, 2005 - genome.cshlp.org
Laboratory evolution can be used to address fundamental questions about adaptation to
selection pressures and, ultimately, the process of evolution. In this study, we investigated …
selection pressures and, ultimately, the process of evolution. In this study, we investigated …