The increasing complexity of in vivo imaging technologies, coupled with the development of
cell therapies, has fuelled a revolution in immune cell tracking in vivo. Powerful magnetic …

Metastatic spread of cancer cells is the main cause of death of breast cancer patients, and
elucidation of the molecular mechanisms underlying this process is a major focus in cancer …

High-grade gliomas are aggressive cancers that often become rapidly fatal. Immunotherapy
using CD8+ cytotoxic T lymphocytes (CTLs), engineered to express both herpes simplex …

Purpose: A phase I study was conducted to assess the safety of adoptive immunotherapy
using gene-modified autologous T cells for the treatment of metastatic ovarian cancer …

Purpose: We previously reported that autologous dendritic cells pulsed with acid-eluted
tumor peptides can stimulate T cell–mediated antitumor immune responses against brain …

Noninvasive molecular-imaging technologies are providing researchers with exciting new
opportunities to study small-animal models of human disease. With continued improvements …

Two genetic reporter systems were developed for multimodality reporter gene imaging of
different molecular-genetic processes using fluorescence, bioluminescence (BLI), and …

Cellular MR imaging is a young field that aims to visualize targeted cells in living organisms.
In order to provide a different signal intensity of the targeted cell, they are either labeled with …

The aim of this study was to assess the efficacy human mesenchymal stem cells (hMSC) for
targeting microscopic tumors and suicide gene or cytokine gene therapy. Immunodeficient …

Most cancer deaths are due to the systemic dissemination of cancer cells and the formation
of secondary tumors (metastasis) in distant organs. Recent years have brought impressive …