Virus infection, antiviral immunity, and autoimmunity

DR Getts, EML Chastain, RL Terry… - Immunological …, 2013 - Wiley Online Library
As a group of disorders, autoimmunity ranks as the third most prevalent cause of morbidity
and mortality in the W estern W orld. However, the etiology of most autoimmune diseases …

Role of pathogens in multiple sclerosis

JE Libbey, MF Cusick, RS Fujinami - International reviews of …, 2014 - Taylor & Francis
Multiple sclerosis (MS) is an inflammatory demyelinating autoimmune disease of the central
nervous system (CNS). Although the etiology of MS is unknown, genetic and environmental …

[PDF][PDF] Acanthamoeba

NA Khan - Biology and pathogenesis, 2009 - caister.com
1. A host for viruses 2. A host for yeast 3. A host for protists 4. Acanthamoeba and bacteria
interactions 5. Is Acanthamoebaan evolutionary ancestor of macrophages? 6 …

[HTML][HTML] Heavy–light chain interrelations of MS-associated immunoglobulins probed by deep sequencing and rational variation

YA Lomakin, MY Zakharova, AV Stepanov… - Molecular …, 2014 - Elsevier
The mechanisms triggering most of autoimmune diseases are still obscure. Autoreactive B
cells play a crucial role in the development of such pathologies and, in particular, production …

SJL Mice Infected with Acanthamoeba castellanii Develop Central Nervous System Autoimmunity through the Generation of Cross-Reactive T Cells for Myelin …

C Massilamany, F Marciano-Cabral, B Rocha-Azevedo… - PloS one, 2014 - journals.plos.org
We recently reported that Acanthamoeba castellanii (ACA), an opportunistic pathogen of the
central nervous system (CNS) possesses mimicry epitopes for proteolipid protein (PLP) 139 …

Branched chain α‐ketoacid dehydrogenase kinase 111–130, a T cell epitope that induces both autoimmune myocarditis and hepatitis in A/J mice

B Krishnan, C Massilamany… - Immunity …, 2017 - Wiley Online Library
Introduction Organ‐specific autoimmune diseases are believed to result from immune
responses generated against self‐antigens specific to each organ. However, when such …

Whole genomic sequence analysis of Bacillus infantis: defining the genetic blueprint of strain NRRL B-14911, an emerging cardiopathogenic microbe

C Massilamany, A Mohammed, JD Loy, T Purvis… - BMC genomics, 2016 - Springer
Background We recently reported the identification of Bacillus sp. NRRL B-14911 that
induces heart autoimmunity by generating cardiac-reactive T cells through molecular …

Copper–zinc superoxide dismutase-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis induced with myelin oligodendrocyte …

C Massilamany, A Gangaplara, H Kim… - Journal of …, 2013 - Elsevier
In this report, we have addressed the role of copper–zinc superoxide dismutase (SOD1)
deficiency in the mediation of central nervous system autoimmunity. We demonstrate that …

A Synthetic View on Acanthamoeba Keratitis Host Immune Response: Potential Factors Influencing the Development of Chronic Inflammation

B Prado-Costa, LF Pinto, MF Fonseca, D de Freitas… - Cornea, 2022 - journals.lww.com
Purpose: The purpose of this study was to compile the current knowledge concerning
Acanthamoeba keratitis (AK) host immune response to better understand the elements …

[PDF][PDF] Epidemiología y diagnóstico de amebas de vida libre implicadas en salud humana

AM Davila - 2014 - docta.ucm.es
Las amebas de vida libre (AVL) como Acanthamoeba o Balamuthia mandrillaris están
consideradas como patógenos emergentes humanos. Estos protozoos tienen formas de …