Human-specific genetics: new tools to explore the molecular and cellular basis of human evolution

AA Pollen, U Kilik, CB Lowe, JG Camp - Nature Reviews Genetics, 2023 - nature.com
Our ancestors acquired morphological, cognitive and metabolic modifications that enabled
humans to colonize diverse habitats, develop extraordinary technologies and reshape the …

Tracing the peopling of the world through genomics

R Nielsen, JM Akey, M Jakobsson, JK Pritchard… - Nature, 2017 - nature.com
Advances in the sequencing and the analysis of the genomes of both modern and ancient
peoples have facilitated a number of breakthroughs in our understanding of human …

[HTML][HTML] A global reference for human genetic variation

1000 Genomes Project Consortium - Nature, 2015 - ncbi.nlm.nih.gov
Abstract The 1000 Genomes Project set out to provide a comprehensive description of
common human genetic variation by applying whole-genome sequencing to a diverse set of …

A rapid method for directed gene knockout for screening in G0 zebrafish

RS Wu, II Lam, H Clay, DN Duong, RC Deo… - Developmental cell, 2018 - cell.com
Zebrafish is a powerful model for forward genetics. Reverse genetic approaches are limited
by the time required to generate stable mutant lines. We describe a system for gene …

Human genetic history on the Tibetan Plateau in the past 5100 years

H Wang, MA Yang, S Wangdue, H Lu, H Chen, L Li… - Science …, 2023 - science.org
Using genome-wide data of 89 ancient individuals dated to 5100 to 100 years before the
present (BP) from 29 sites across the Tibetan Plateau, we found plateau-specific ancestry …

Loci associated with skin pigmentation identified in African populations

NG Crawford, DE Kelly, MEB Hansen, MH Beltrame… - Science, 2017 - science.org
INTRODUCTION Variation in pigmentation among human populations may reflect local
adaptation to regional light environments, because dark skin is more photoprotective …

Clinical and biological characterization of skin pigmentation diversity and its consequences on UV impact

S Del Bino, C Duval, F Bernerd - International journal of molecular …, 2018 - mdpi.com
Skin color diversity is the most variable and noticeable phenotypic trait in humans resulting
from constitutive pigmentation variability. This paper will review the characterization of skin …

Upper Palaeolithic genomes reveal deep roots of modern Eurasians

ER Jones, G Gonzalez-Fortes, S Connell… - Nature …, 2015 - nature.com
We extend the scope of European palaeogenomics by sequencing the genomes of Late
Upper Palaeolithic (13,300 years old, 1.4-fold coverage) and Mesolithic (9,700 years old …

The HIrisPlex-S system for eye, hair and skin colour prediction from DNA: Introduction and forensic developmental validation

L Chaitanya, K Breslin, S Zuñiga, L Wirken… - Forensic Science …, 2018 - Elsevier
Abstract Forensic DNA Phenotyping (FDP), ie the prediction of human externally visible traits
from DNA, has become a fast growing subfield within forensic genetics due to the …

Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system

LE Jao, SR Wente, W Chen - Proceedings of the National …, 2013 - National Acad Sciences
A simple and robust method for targeted mutagenesis in zebrafish has long been sought.
Previous methods generate monoallelic mutations in the germ line of F0 animals, usually …