Lipoxygenases (LOXs) form a heterogeneous class of lipid peroxidizing enzymes, which
have been implicated not only in cell proliferation and differentiation but also in the …

As a lipoxygenase (LOX), arachidonate 15-lipoxygenase type B (ALOX15B) peroxidizes
polyenoic fatty acids (PUFAs) including arachidonic acid (AA), eicosapentaenoic acid (EPA) …

Arachidonic acid (ARA) undergoes enzyme-mediated oxidative metabolism, resulting in the
formation of a number of biologically active metabolites. For over a century, these …

5-lipoxygenase (5-LOX) is a non-heme iron-containing dioxygenase expressed in immune
cells that catalyzes the two initial steps in the biosynthesis of leukotrienes. It is well known …

There are a variety of lipoxygenases in the human body (hLO), each having a distinct role in
cellular biology. Human reticulocyte 15-lipoxygenase-1 (15-hLO-1), which catalyzes the …

The oxylipins, 5S, 12S-dihydroxy-6E, 8Z, 10E, 14Z-eicosatetraenoic acid (5S, 12S-diHETE)
and 5S, 15S-dihydroxy-6E, 8Z, 11Z, 13E-eicosatetraenoic acid (5S, 15S-diHETE), have …

Human reticulocyte 15-lipoxygenase-1 (h15-LOX-1 or ALOX15) and platelet 12-
lipoxygenase (h12-LOX or ALOX12) catalysis of docosahexaenoic acid (DHA) and the …

Lipoxygenases (LOXs) catalyze the (per) oxidation of fatty acids that serve as important
mediators for cell signaling and inflammation. These reactions are initiated by a CH …

Lipoxygenases catalyze the peroxidation of poly-unsaturated fatty acid chains either free or
esterified in membrane lipids. Vitis vinifera LoxA is transcriptionally induced at ripening …

Abstract Human 5-lipoxygenase (5-LO) can form dimers as shown here via native gel
electrophoresis, gel filtration chromatography and LILBID (laser induced liquid bead ion …