The accumulation of adipose tissue in the body occurs because the energy introduced with
food and drink exceeds that expense, but to understand why this imbalance is established …

Oral squamous cell carcinoma (OSCC) has a high propensity for local failure, which is
attributed to recurrence at the primary site or the development of second primary tumors …

Immune responses against thyroid carcinomas have long been demonstrated and
associations between inflammatory microenvironment and thyroid carcinomas repeatedly …

Sirtuins participate in hormone imbalance, metabolism and aging, which are important
processes for endometrial cancer (EC) development. Sirtuins mRNA expression (SIRT1 to 7) …

Background Undifferentiated/dedifferentiated endometrial carcinoma (UEC/DDEC) is a
heterogeneous entity, which may show any of the TCGA molecular signatures and loss of …

Epigenetic alterations, including aberrant DNA methylation, play an important role in human
cancer development. Importantly, epigenetic alterations are reversible and can be targets for …

Abnormal methylation of secreted frizzled‑related proteins (SFRPs) has been observed in
various human cancer types. The loss of SFRP gene expression induces the activation of …

Endometrial cancer is the most common gynaecological malignancy in developed nations,
and its prevalence is rising as women defer or decide not to have children and as obesity …

Oral cancers have been proven to arise from precursors lesions and to be related to risk
behaviour such as alcohol consumption and smoke. However, the present paper focuses on …

Objective Hypoalbuminemia, a known marker for malnutrition and increased morbidity and
mortality, has been associated with impaired prognosis in different cancer entities. The …