Unlocking the magic in mycelium: Using synthetic biology to optimize filamentous fungi for biomanufacturing and sustainability

C Jo, J Zhang, JM Tam, GM Church, AS Khalil… - Materials Today Bio, 2023 - Elsevier
Filamentous fungi drive carbon and nutrient cycling across our global ecosystems, through
its interactions with growing and decaying flora and their constituent microbiomes. The …

Heterologous protein production in filamentous fungi

D Liu, S Garrigues, RP de Vries - Applied microbiology and biotechnology, 2023 - Springer
Filamentous fungi are able to produce a wide range of valuable proteins and enzymes for
many industrial applications. Recent advances in fungal genomics and experimental …

Precision cellular agriculture: The future role of recombinantly expressed protein as food

JH Dupuis, LKY Cheung, L Newman… - … Reviews in Food …, 2023 - Wiley Online Library
Cellular agriculture is a rapidly emerging field, within which cultured meat has attracted the
majority of media attention in recent years. An equally promising area of cellular agriculture …

Engineering interventions in industrial filamentous fungal cell factories for biomass valorization

A Madhavan, KB Arun, R Sindhu, AA Jose… - Bioresource …, 2022 - Elsevier
Filamentous fungi possess versatile capabilities for synthesizing a variety of valuable bio
compounds, including enzymes, organic acids and small molecule secondary metabolites …

[HTML][HTML] Fungal cell factories for efficient and sustainable production of proteins and peptides

M Lübeck, PS Lübeck - Microorganisms, 2022 - mdpi.com
Filamentous fungi are a large and diverse taxonomically group of microorganisms found in
all habitats worldwide. They grow as a network of cells called hyphae. Since filamentous …

The phenomenon of strain degeneration in biotechnologically relevant fungi

C Danner, RL Mach, AR Mach-Aigner - Applied Microbiology and …, 2023 - Springer
Fungi are widely exploited for large-scale production in the biotechnological industry to
produce a diverse range of substances due to their versatility and relative ease of growing …

Regulators of the Asexual Life Cycle of Aspergillus nidulans

YE Son, JH Yu, HS Park - Cells, 2023 - mdpi.com
The genus Aspergillus, one of the most abundant airborne fungi, is classified into hundreds
of species that affect humans, animals, and plants. Among these, Aspergillus nidulans, as a …

Exploration of the Strategy for Improving the Expression of Heterologous Sweet Protein Monellin in Aspergillus niger

K Li, J Zheng, L Yu, B Wang, L Pan - Journal of Fungi, 2023 - mdpi.com
Aspergillus niger is a primary cell factory for food-grade protein (enzyme) production due to
its strong protein secretion capacity and unique safety characteristics. The bottleneck issue …

New insights into genome annotation in Podospora anserina through re-exploiting multiple RNA-seq data

G Lelandais, D Remy, F Malagnac, P Grognet - BMC genomics, 2022 - Springer
Background Publicly available RNA-seq datasets are often underused although being
helpful to improve functional annotation of eukaryotic genomes. This is especially true for …

Enhancing the production of a heterologous Trametes laccase (LacA) by replacement of the major cellulase CBH1 in Trichoderma reesei

J Zhang, Y Hong, K Li, Y Sun, C Yao… - Journal of Industrial …, 2023 - academic.oup.com
The laccases from white-rot fungi exhibit high redox potential in treating phenolic
compounds. However, their application in commercial purposes has been limited because …