Traumatic brain injury (TBI) is one of the most common diseases in the central nervous
system (CNS) with high mortality and morbidity. Patients with TBI usually suffer many …

Peroxisome proliferator-activated receptor gamma (PPARγ) has been implicated in the
pathology of numerous diseases involving diabetes, stroke, cancer, or obesity. It is …

Pioglitazone, an FDA-approved compound, has been shown to target the novel
mitochondrial protein mitoNEET and produce short-term neuroprotection and functional …

Traumatic brain injury (TBI) is still a major cause of concern for public health, and out of all
the trauma‐related injuries, it makes the highest contribution to death and disability …

Cerebral edema is commonly associated with cerebral pathology, and the clinical
manifestation is largely related to the underlying lesioned tissue. Brain edema usually …

Traumatic brain injury (TBI) has become one of the most important causes of death and
disability worldwide. A series of neuroinflammatory responses induced after TBI are key …

Traumatic brain injury (TBI) constitutes a major health problem worldwide and is a leading
cause of death and disability in individuals, contributing to devastating socioeconomic …

Increasing evidence indicates that activated microglia play an important role in the
inflammatory response following traumatic brain injury (TBI). Inhibiting M1 and stimulating …

Microglia have been implicated as a key mediator of chronic inflammation following
traumatic brain injury (TBI). The animal models of TBI vary significantly based on the type of …

Recent findings have led to the discovery of many signaling pathways that link nuclear
receptors with human conditions, including mental decline and neurodegenerative …