Periodontitis, a microbiome‐driven inflammatory disease of the tooth‐attachment apparatus,
is epidemiologically linked with other disorders, including cardio‐metabolic, cognitive …

Since human skin is an immune organ, a large number of immune cells are distributed in the
epidermis and the dermis of the skin. Transdermal immunotherapy shows great therapeutic …

Periodontitis is a chronic infectious disease caused by bacterial irritation. As an essential
component of the host immunity, macrophages are highly plastic and play a crucial role in …

Periodontitis is a chronic, inflammatory, and destructive disease caused by the imbalance of
host immune response and dental biofilm, and has strong epidemiological and …

Periodontitis is a chronic inflammatory disease caused by the local microbiome and the host
immune response, resulting in periodontal structure damage and even tooth loss. Scaling …

Bacteria eradication and subsequent periodontal tissue reconstruction is the primary task for
periodontitis treatment. Commonly used antibiotic therapy suffers from antibiotic resistance …

Both absent in melanoma 2 (AIM2) and interferon-inducible protein 16 (IFI16) are
intracellular innate immune receptors that recognize double-stranded DNA released during …

Objective To identify, quantify, and characterize leukocyte populations in PI and periodontitis
using flow cytometry. Methods Fresh biopsies from human PI and periodontitis lesions were …

Periodontitis is a prevalent disease and one of the leading causes of tooth loss. Biofilms are
initiating factor of periodontitis, which can destroy periodontal tissue by producing virulence …

Self-tolerance involves protection from self-reactive B and T cells via negative selection
during differentiation, programmed cell death, and inhibition of regulatory T cells. The …