Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors

I Jurado-Martín, M Sainz-Mejías… - International journal of …, 2021 - mdpi.com
Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF)
contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its …

[HTML][HTML] How to manage Pseudomonas aeruginosa infections

M Bassetti, A Vena, A Croxatto, E Righi, B Guery - Drugs in context, 2018 - ncbi.nlm.nih.gov
Infections with Pseudomonas aeruginosa have become a real concern in hospital-acquired
infections, especially in critically ill and immunocompromised patients. The major problem …

[HTML][HTML] Metabolite interactions between host and microbiota during health and disease: Which feeds the other?

Y Zhang, R Chen, DD Zhang, S Qi, Y Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Metabolites produced by the host and microbiota play a crucial role in how human bodies
develop and remain healthy. Most of these metabolites are produced by microbiota and …

Immunometabolic crosstalk during bacterial infection

G Rosenberg, S Riquelme, A Prince, R Avraham - Nature microbiology, 2022 - nature.com
Following detection of bacteria, macrophages switch their metabolism from oxidative
respiration through the tricarboxylic acid cycle to high-rate aerobic glycolysis. This …

Update of the treatment of nosocomial pneumonia in the ICU

R Zaragoza, P Vidal-Cortés, G Aguilar, M Borges… - Critical Care, 2020 - Springer
In accordance with the recommendations of, amongst others, the Surviving Sepsis
Campaign and the recently published European treatment guidelines for hospital-acquired …

Multidrug-resistant bacteria and alternative methods to control them: an overview

R Vivas, AAT Barbosa, SS Dolabela… - Microbial Drug …, 2019 - liebertpub.com
Antibiotic resistance is one of the greatest challenges in the health system nowadays,
representing a serious problem for public health. Initially, antibiotic-resistant strains were …

Impact of multi-drug resistant bacteria on economic and clinical outcomes of healthcare-associated infections in adults: Systematic review and meta-analysis

M Serra-Burriel, M Keys, C Campillo-Artero, A Agodi… - PloS one, 2020 - journals.plos.org
Background Infections with multidrug resistant (MDR) bacteria in hospital settings have
substantial implications in terms of clinical and economic outcomes. However, due to clinical …

The environmental occurrence of Pseudomonas aeruginosa

S Crone, M Vives‐Flórez, L Kvich, AM Saunders… - Apmis, 2020 - Wiley Online Library
Pseudomonas aeruginosa is generally described as ubiquitous in natural settings, such as
soil and water. However, because anecdotal observations and published reports have …

Pseudomonas aeruginosa utilizes host-derived itaconate to redirect its metabolism to promote biofilm formation

SA Riquelme, K Liimatta, TWF Lung, B Fields, D Ahn… - Cell metabolism, 2020 - cell.com
The bacterium Pseudomonas aeruginosa is especially pathogenic, often being associated
with intractable pneumonia and high mortality. How P. aeruginosa avoids immune clearance …

Ceftolozane-Tazobactam for the Treatment of Multidrug-Resistant Pseudomonas aeruginosa Infections: Clinical Effectiveness and Evolution of Resistance

G Haidar, NJ Philips, RK Shields… - Clinical Infectious …, 2017 - academic.oup.com
Background Data on the use of ceftolozane-tazobactam and emergence of ceftolozane-
tazobactam resistance during multidrug resistant (MDR)-Pseudomonas aeruginosa …