Changing epidemiology of hepatocellular carcinoma in Asia

C Zhang, Y Cheng, S Zhang, J Fan, Q Gao - Liver International, 2022 - Wiley Online Library
Liver cancer is the fifth most common cancer and the second leading cause of malignant
death in Asia, and Asia reports 72.5% of the world's cases in 2020. As the most common …

Nasal route for vaccine and drug delivery: Features and current opportunities

YL Mato - International journal of pharmaceutics, 2019 - Elsevier
Mucosal administration, and specifically nasal route, constitutes an alternative and
promising strategy for drug and vaccine delivery. Mucosal routes have several advantages …

Advances in intranasal vaccine delivery: A promising non-invasive route of immunization

E Kehagia, P Papakyriakopoulou, G Valsami - Vaccine, 2023 - Elsevier
The importance of vaccination has been proven particularly significant the last three years,
as it is revealed to be the most efficient weapon for the prevention of several infections …

Advances in targeting the innate and adaptive immune systems to cure chronic hepatitis B virus infection

Z Meng, Y Chen, M Lu - Frontiers in Immunology, 2020 - frontiersin.org
“Functional cure” is being pursued as the ultimate endpoint of antiviral treatment in chronic
hepatitis B (CHB), which is characterized by loss of HBsAg whether or not anti-HBs …

[HTML][HTML] Hepatitis B vaccine and immunoglobulin: key concepts

S Das, K Ramakrishnan, SK Behera… - Journal of clinical and …, 2019 - ncbi.nlm.nih.gov
Hepatitis B virus (HBV) immunization is safe and has been accepted worldwide as a routine
practice. The target of such vaccination is to induce the immune response in the host …

Therapeutic vaccination for treatment of chronic hepatitis B

T Cargill, E Barnes - Clinical & Experimental Immunology, 2021 - academic.oup.com
Chronic hepatitis B infection remains a serious global health threat, contributing to a large
number of deaths through liver cirrhosis and hepatocellular carcinoma. Current treatment …

New approaches to the treatment of chronic hepatitis B

A Alexopoulou, L Vasilieva, P Karayiannis - Journal of Clinical Medicine, 2020 - mdpi.com
The currently recommended treatment for chronic hepatitis B virus (HBV) infection achieves
only viral suppression whilst on therapy, but rarely hepatitis B surface antigen (HBsAg) loss …

Novel therapeutic strategies for chronic hepatitis B

S Phillips, R Jagatia, S Chokshi - Virulence, 2022 - Taylor & Francis
The last few years have seen a resurgence of activity in the hepatitis B drug pipeline, with
many compounds in various stages of development. This review aims to provide a …

[HTML][HTML] Toward a new era of hepatitis B virus therapeutics: The pursuit of a functional cure

EP Tsounis, E Tourkochristou, A Mouzaki… - World journal of …, 2021 - ncbi.nlm.nih.gov
Hepatitis B virus (HBV) infection, although preventable by vaccination, remains a global
health problem and a major cause of chronic liver disease. Although current treatment …

HBV infection and host interactions: the role in viral persistence and oncogenesis

R Nevola, D Beccia, V Rosato, R Ruocco… - International Journal of …, 2023 - mdpi.com
Hepatitis B virus (HBV) is a major cause of chronic hepatitis, liver cirrhosis, and
hepatocellular carcinoma. Despite the advent of vaccines and potent antiviral agents able to …