Angiogenesis, the formation of new blood vessels, is a complex and dynamic process
regulated by various pro-and anti-angiogenic molecules, which plays a crucial role in tumor …

Fibroblasts play an essential role in organogenesis and the integrity of tissue architecture
and function. Growth in most solid tumors is dependent upon remodeling 'stroma', composed …

Photodynamic therapy (PDT) is a clinically approved cancer therapy, based on a
photochemical reaction between a light activatable molecule or photosensitizer, light, and …

Ethnopharmacological relevance Melissa officinalis L. is a medicinal plant that has long
been used in different ethno-medical systems especially in the European Traditional …

The role of angiogenesis in tumor growth has been studied continuously for over 45 years. It
is now appreciated that angiogenesis is also essential for the dissemination and …

Abrogating tumor angiogenesis by inhibiting vascular endothelial growth factor receptor‐2
(VEGFR 2) has been established as a therapeutic strategy for treating cancer. However …

Angiogenesis is a critical step in the progression of almost all human malignancies and
some other life-threatening diseases. Anti-angiogenic therapy is a novel and effective …

Ipilimumab improves survival in advanced melanoma and can induce immune-mediated
tumor vasculopathy. Besides promoting angiogenesis, vascular endothelial growth factor …

Compared with traditional chemotherapeutics, vascular disruption agents (VDAs) have the
advantages of rapidly blocking the supply of nutrients and starving tumors to death. Although …

Osteosarcoma (OS), the most common type of primary malignant bone tumor, is defined by
the presence of malignant mesenchymal cells producing osteoid or immature bone. The …