Nanoparticles, proteins, and nucleic acids: biotechnology meets materials science

CM Niemeyer - Angewandte Chemie International Edition, 2001 - Wiley Online Library
Based on fundamental chemistry, biotechnology and materials science have developed
over the past three decades into today's powerful disciplines which allow the engineering of …

Integrated nanoparticle–biomolecule hybrid systems: synthesis, properties, and applications

E Katz, I Willner - Angewandte Chemie International Edition, 2004 - Wiley Online Library
Nanomaterials, such as metal or semiconductor nanoparticles and nanorods, exhibit similar
dimensions to those of biomolecules, such as proteins (enzymes, antigens, antibodies) or …

Deciphering epiblast lumenogenesis reveals proamniotic cavity control of embryo growth and patterning

YS Kim, R Fan, L Kremer, N Kuempel-Rink… - Science …, 2021 - science.org
During the peri-implantation stages, the mouse embryo radically changes its appearance,
transforming from a hollow-shaped blastocyst to an egg cylinder. At the same time, the …

Dynamic DNA hybridization on a chip using paramagnetic beads

ZH Fan, S Mangru, R Granzow, P Heaney… - Analytical …, 1999 - ACS Publications
Dynamic DNA hybridization is presented as an approach to perform gene expression
analysis. The method is advantageous because of its dynamic supplies of both DNA …

Integrierte Hybridsysteme aus Nanopartikeln und Biomolekülen: Synthese, Eigenschaften und Anwendungen

E Katz, I Willner - Angewandte Chemie, 2004 - Wiley Online Library
Abstract Metall‐oder Halbleiter‐Nanopartikel und Nanostäbchen haben ähnliche
Dimensionen wie Proteine (Enzyme, Antigene, Antikörper) oder DNA. Die Integration von …

[HTML][HTML] Plug-and-play pairing via defined divalent streptavidins

M Fairhead, D Krndija, ED Lowe, M Howarth - Journal of molecular biology, 2014 - Elsevier
Streptavidin is one of the most important hubs for molecular biology, either multimerizing
biomolecules, bridging one molecule to another, or anchoring to a biotinylated …

A hexameric helicase encircles one DNA strand and excludes the other during DNA unwinding

KJ Hacker, KA Johnson - Biochemistry, 1997 - ACS Publications
The bacteriophage T7 DNA helicase/primase (gene 4 protein) is a ring-like hexamer that
encircles ssDNA and requires forked DNA to catalyze DNA unwinding. We report that …

Reduced antibody response to streptavidin through site‐directed mutagenesis

DL Meyer, J Schultz, Y Lin, A Henry… - Protein …, 2001 - Wiley Online Library
Streptavidin provides an effective receptor for biotinylated tumoricidal molecules, including
radionuclides, when conjugated to an antitumor antibody and administered systemically …

Traceless purification and desulfurization of tau protein ligation products

O Reimann, C Smet‐Nocca… - Angewandte Chemie …, 2015 - Wiley Online Library
We present a novel strategy for the traceless purification and synthetic modification of
peptides and proteins obtained by native chemical ligation. The strategy involves …

Tamavidins–novel avidin‐like biotin‐binding proteins from the Tamogitake mushroom

Y Takakura, M Tsunashima, J Suzuki… - The FEBS …, 2009 - Wiley Online Library
Novel biotin‐binding proteins, referred to herein as tamavidin 1 and tamavidin 2, were found
in a basidiomycete fungus, Pleurotus cornucopiae, known as the Tamogitake mushroom …