Pathophysiology of atherosclerosis

S Jebari-Benslaiman, U Galicia-García… - International journal of …, 2022 - mdpi.com
Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …

Role of lipid accumulation and inflammation in atherosclerosis: focus on molecular and cellular mechanisms

K Malekmohammad, EE Bezsonov… - Frontiers in …, 2021 - frontiersin.org
Atherosclerosis is a chronic lipid-driven and maladaptive inflammatory disease of arterial
intima. It is characterized by the dysfunction of lipid homeostasis and signaling pathways …

Calcific aortic valve disease: from molecular and cellular mechanisms to medical therapy

S Kraler, MC Blaser, E Aikawa, GG Camici… - European heart …, 2022 - academic.oup.com
Calcific aortic valve disease (CAVD) is a highly prevalent condition that comprises a disease
continuum, ranging from microscopic changes to profound fibro-calcific leaflet remodelling …

Therapeutic potential of colchicine in cardiovascular medicine: a pharmacological review

FS Zhang, QZ He, CH Qin, PJ Little, JP Weng… - Acta Pharmacologica …, 2022 - nature.com
Colchicine is an ancient herbal drug derived from Colchicum autumnale. It was first used to
treat familial Mediterranean fever and gout. Based on its unique efficacy as an anti …

New insight into dyslipidemia‐induced cellular senescence in atherosclerosis

Q Xiang, F Tian, J Xu, X Du, S Zhang… - Biological Reviews, 2022 - Wiley Online Library
Atherosclerosis, characterized by lipid‐rich plaques in the arterial wall, is an age‐related
disorder and a leading cause of mortality worldwide. However, the specific mechanisms …

Berberine: a review of its pharmacokinetics properties and therapeutic potentials in diverse vascular diseases

X Ai, P Yu, L Peng, L Luo, J Liu, S Li, X Lai… - Frontiers in …, 2021 - frontiersin.org
Traditional Chinese medicine plays a significant role in the treatment of various diseases
and has attracted increasing attention for clinical applications. Vascular diseases affecting …

[HTML][HTML] Abnormalities of glucose and lipid metabolism in myocardial ischemia-reperfusion injury

H Tian, X Zhao, Y Zhang, Z Xia - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Myocardial ischemia-reperfusion injury is a common condition in cardiovascular diseases,
and the mechanism of its occurrence involves multiple complex metabolic pathways and …

Soluble lectin-like oxidized low-density lipoprotein receptor-1 predicts premature death in acute coronary syndromes

S Kraler, FA Wenzl, G Georgiopoulos… - European heart …, 2022 - academic.oup.com
Aims The lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) and its shedding
product [soluble LOX-1 (sLOX-1)] are implicated in atherosclerotic cardiovascular disease …

Inflammation, oxidative stress, vascular aging and atherosclerotic ischemic stroke

IK Koutsaliaris, IC Moschonas… - Current Medicinal …, 2022 - ingentaconnect.com
Vascular aging is a crucial risk factor for atherosclerotic ischemic stroke. Vascular aging is
characterized by oxidative stress, endothelial dysfunction, inflammation, intimal and media …

[HTML][HTML] Protective effects of oleic acid and polyphenols in extra virgin olive oil on cardiovascular diseases

Y Lu, J Zhao, Q Xin, R Yuan, Y Miao, M Yang… - Food Science and …, 2024 - Elsevier
The Mediterranean diet has long been recognized as one of the most effective ways to
prevent and improve cardiovascular disease. Extra virgin olive oil (EVOO) is the typical …